D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester

Base Information

Chemical Name:D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester
CAS No.:15136-32-0
Molecular Formula:C21H32N2O5
Molecular Weight:392.495
Hs Code.:
DSSTox Substance ID:DTXSID601154799
Mol file:15136-32-0.mol

Synonyms:15136-32-0;DTXSID601154799;D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester;D-Phenylalanine,N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-,Methyl ester;N-[(1,1-Dimethylethoxy)carbonyl]-L-leucyl-D-phenylalanine methyl ester

Suppliers and Price of D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:11
Exact Mass:392.23112213
Heavy Atom Count:28
Complexity:521

Purity/Quality:: ≥95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)CC(C(=O)NC(CC1=CC=CC=C1)C(=O)OC)NC(=O)OC(C)(C)C
Isomeric SMILES:CC(C)C[C@@H](C(=O)N[C@H](CC1=CC=CC=C1)C(=O)OC)NC(=O)OC(C)(C)C

Technology Process of D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester

There total 21 articles about D-Phenylalanine, N-[(1,1-diMethylethoxy)carbonyl]-L-leucyl-, Methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 7524-50-7
methyl (2S)-2-amino-3-phenylpropanoate hydrochloride

: 200937-21-9
N-tert-butoxycarbonyl-L-leucine monohydrate

: 15136-32-0,87976-66-7,120342-25-8,5874-73-7
(N-(tert-butoxycarbonyl)-L-leucinyl)-L-phenylalanine methyl ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate; In N,N-dimethyl-formamide; at 20 ℃; for 18h; Inert atmosphere;
DOI:10.1016/j.bmcl.2018.12.032

Reference yield: 99.0%

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 2577-90-4
methyl (2S)-2-amino-3-phenylpropanoate

: 15136-32-0,87976-66-7,120342-25-8,5874-73-7
(N-(tert-butoxycarbonyl)-L-leucinyl)-L-phenylalanine methyl ester

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2009.07.017

Reference yield: 99.0%

: 13139-15-6,53296-34-7
N-tert-butoxycarbonyl-L-leucine

: 21685-51-8
D-phenylalanine methyl ester

: 15136-32-0
Boc-L-Leu-D-Phe-OMe

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; N-ethyl-N,N-diisopropylamine; In dichloromethane; acetonitrile; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2010.07.042