Benzoic acid, 4,5-dimethoxy-2-methyl-, ethyl ester

Base Information

• Chemical Name: Benzoic acid, 4,5-dimethoxy-2-methyl-, ethyl ester
• CAS No.: 15364-83-7
• Molecular Formula: C12H16O4
• Molecular Weight: 224.25300
• Mol file: 15364-83-7.mol

Synonyms:4,5-Dimethoxy-2-methyl-benzoesaeure-aethylester;4.5-Dimethoxy-o-toluylsaeureethylester;Benzoic acid,4,5-dimethoxy-2-methyl-,ethyl ester;

Chemical Property of Benzoic acid, 4,5-dimethoxy-2-methyl-, ethyl ester

Chemical Property:

• PSA: 44.76000
• LogP: 2.18890

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzoic acid, 4,5-dimethoxy-2-methyl-, ethyl ester

There total 4 articles about Benzoic acid, 4,5-dimethoxy-2-methyl-, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methyl-4,5-dimethoxybenzaldehyde (24186-66-1) → 4,5-Dimethoxy-2-methyl-benzoesaeure-aethylester (15364-83-7)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. NaOBr / dioxane

2: H₂SO₄

With sodium hypobromide; sulfuric acid; In 1,4-dioxane;

DOI:10.1021/jo01266a004

Reference yield:

1,2-dimethoxy-4-methylbenzene (494-99-5) → 4,5-Dimethoxy-2-methyl-benzoesaeure-aethylester (15364-83-7)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃

2: aq. NaOBr / dioxane

3: H₂SO₄

With aluminium trichloride; sodium hypobromide; sulfuric acid; In 1,4-dioxane;

DOI:10.1021/jo01266a004

Reference yield:

ethanol (64-17-5) + 4,5-dimethoxy-2-methylbenzoic acid (20736-28-1,131035-49-9) → 4,5-Dimethoxy-2-methyl-benzoesaeure-aethylester (15364-83-7)

Guidance literature:

With sulfuric acid;

DOI:10.1021/jo01266a004

upstream raw materials:

ethanol

4,5-dimethoxy-2-methylbenzoic acid

2-methyl-4,5-dimethoxybenzaldehyde

1,2-dimethoxy-4-methylbenzene

Downstream raw materials:

2-(bromomethyl)-4,5-dimethoxybenzoic acid ethyl ester