24186-66-1

Basic information

• Product Name: 1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHAN-1-ONE
• Synonyms: 1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHAN-1-ONE;1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHANONE;4,5-DIMETHOXY-2-METHYLACETOPHENONE
• CAS NO: 24186-66-1
• Molecular Formula: C₁₁H₁₄O₃
• Molecular Weight: 194.23
• Mol File: 24186-66-1.mol
• Article Data: 3

Chemical Properties

• Melting Point: 68 °C
• Boiling Point: 301.4±37.0 °C(Predicted)
• Appearance: /
• Density: 1.048±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHAN-1-ONE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHAN-1-ONE(24186-66-1)
• EPA Substance Registry System: 1-(4,5-DIMETHOXY-2-METHYLPHENYL)ETHAN-1-ONE(24186-66-1)

Safety Data

• Hazard Codes: Xi
• Hazardous Substances Data: 24186-66-1(Hazardous Substances Data)

Usage

Preparation

Obtained from 4-methylveratrole by reaction, ? with acetyl chloride in the presence of aluminium chloride in carbon disulfide ; ? with acetic anhydride in the presence of aluminium chloride in tetrachloroethane.

Upstream product

• 494-99-5 1,2-dimethoxy-4-methylbenzene 
• 75-36-5 acetyl chloride 
• 144369-40-4 N,O-dimethyl-4,5-dimethoxy-2-iodobenzylamide 
• 155955-78-5 3,4-dimethoxyphenylacetic acid N,O-dimethylhydroxyamide 
• 93-40-3 (3,4-Dimethoxyphenyl)acetic acid 
• 2632-13-5 2-Bromo-4'-methoxyacetophenone 
• 93624-01-2 O-ethyl S-2-(4-methoxyphenyl)-2-oxoethyl carbonodithioate 
• 1334498-64-4 S-(2-(4,5-dimethoxy-2-methylphenyl)-2-oxoethyl) O-ethyl carbonodithioate 
• 93-51-6 2-Methoxy-4-methylphenol 
• 64-19-7 acetic acid 
• 162853-20-5 1-(4-hydroxy-5-methoxy-2-methyl-phenyl)-ethanone 
• 77-78-1 dimethyl sulfate 
• 75-15-0 carbon disulfide 
• 7446-70-0 aluminium trichloride 

Downstream Products

• 143141-90-6 (E,E)-di-<2-methyl-4,5-dimethoxybenzylidene>-succinic acid 
• 408534-24-7 4,5-dimethoxy-2-oxalyl-benzoic acid 
• 871899-50-2 (4,5-dimethoxy-2-methyl-phenyl)-glyoxylic acid 
• 577-68-4 m-hemipinic acid 
• 144-62-7 oxalic acid 
• 52806-46-9 1-bromo-4,5-dimethoxy-2-methylbenzene 
• 15365-26-1 2-(bromomethyl)-4,5-dimethoxybenzoic acid ethyl ester 
• 15364-83-7 4,5-Dimethoxy-2-methyl-benzoesaeure-aethylester 
• 24186-67-2 2-(4,5-Dimethoxy-2-methoxycarbonyl)phenyl-2-oxoessigsaeuremethylester 
• 17078-61-4 dimethyl 3,4-dimethoxy-1,6-benzenedicarboxylate 
• 18087-16-6 4-ethyl-5-methyl-pyrocatechol 
• 143141-91-7 (E,E)-di-<2-methyl-4,5-dimethoxybenzylidene>-succinic anhydride 
• 143141-89-3 diethyl (E)-2-methyl-4,5-dimethoxybenzylidene-succinate 
• 143141-88-2 (E)-2-methyl-4,5-dimethoxybenzylidene-succinic acid 

Relevant articles and documents

Facile o-quinodimethane formation from benzocyclobutenes triggered by the Staudinger reaction at ambient temperature

Electron-donating iminophosphoranes were found to significantly enhance 4π-ring opening of benzocyclobutenes to generate o-quinodimethanes at 20-25 °C. These iminophosphorane benzocyclobutenes can be conveniently generated from azide benzocyclobutenes and phosphines via the Staudinger reaction. Thus, Staudinger reaction-triggered sequential molecular transformations of the azide benzocyclobutenes have been established via o-quinodimethanes at ambient temperature, which is expected to exhibit potential for a wide range of applications.

Total synthesis of aristolactams via a one-pot Suzuki-Miyaura coupling/aldol condensation cascade reaction

(Chemical Equation Presented) A direct one-pot synthesis of phenanthrene lactams, which employs a Suzuki -Miyaura coupling/aldol condensation cascade reaction of isoindolin-1-one with 2-formylphenylboronic acid, has been developed. The approach is used to