4-(1-Methylcyclopentyl)phenol

Base Information

• Chemical Name: 4-(1-Methylcyclopentyl)phenol
• CAS No.: 1562-25-0
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• DSSTox Substance ID: DTXSID70496794
• Nikkaji Number: J801.710G
• Wikidata: Q82345906
• Mol file: 1562-25-0.mol

Synonyms:4-(1-Methylcyclopentyl)phenol;1562-25-0;Phenol, 4-(1-methylcyclopentyl)-;4-(1-methylcyclopentan-1-yl)phenol;p-(1-methylcyclopentyl)phenol;SCHEMBL5241008;4-(1-methyl-cyclopentyl)-phenol;DTXSID70496794;XQDKIMZRWNYNOI-UHFFFAOYSA-N

Chemical Property of 4-(1-Methylcyclopentyl)phenol

Chemical Property:

• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 176.120115130
• Heavy Atom Count: 13
• Complexity: 162

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(CCCC1)C2=CC=C(C=C2)O

Technology Process of 4-(1-Methylcyclopentyl)phenol

There total 4 articles about 4-(1-Methylcyclopentyl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.4%

1-methylcyclopent-1-ene (693-89-0) + phenol (108-95-2,27073-41-2) → 4-(1-methylcyclopentan-1-yl)phenol (1562-25-0)

Guidance literature:

With zeolite-P; at 80 ℃; for 3h;

DOI:10.1134/S0965544107060059

Reference yield:

1-chloro-1-methylcyclopentane (6196-85-6) + phenol (108-95-2,27073-41-2) → 4-(1-methylcyclopentan-1-yl)phenol (1562-25-0)

Guidance literature:

at 150 ℃;

DOI:10.1021/ja01192a047

Reference yield:

aluminium trichloride (7446-70-0) + 1-chloro-1-methylcyclopentane (6196-85-6) + phenol (108-95-2,27073-41-2) → 4-(1-methylcyclopentan-1-yl)phenol (1562-25-0)

Guidance literature:

at 20 ℃;

upstream raw materials:

1-chloro-1-methylcyclopentane

phenol

1-methylcyclopent-1-ene

aluminium trichloride

Downstream raw materials:

2-Chloro-N-[2-hydroxy-5-(1-methyl-cyclopentyl)-benzyl]-acetamide

2-(aminomethyl)-4-(1-methylcyclopentyl)phenol hydrochloride

2-Aminomethyl-6-iodo-4-(1-methyl-cyclopentyl)-phenol; hydrochloride