CHX-A''-DTPA(B-355)

Base Information

Chemical Name:CHX-A''-DTPA(B-355)
CAS No.:157380-45-5
Molecular Formula:C₂₆H₃₄N₄O₁₀S
Molecular Weight:594.643
Hs Code.:
Mol file:157380-45-5.mol

Synonyms:Glycine, N-[(1S,2S)-2-[bis(carboxymethyl)amino]cyclohexyl]-N-[(2R)-2-[bis(carboxymethyl)amino]-3-(4-isothiocyanatophenyl)propyl]-;CHX-A''-DTPA;CITC-CHXA''DTPA;Glycine, N-[2-[bis(carboxymethyl)amino]cyclohexyl]-N-[2-[bis(carboxymethyl)amino]-3-(4-isothiocyanatophenyl)propyl]-, [1S-[1α(S*),2β]]-;N-[(1S,2S)-2-[Bis(carboxymethyl)amino]cyclohexyl]-N-[(2R)-2-[bis(carboxymethyl)amino]-3-(4-isothiocyanatophenyl)propyl]glycine;

Suppliers and Price of CHX-A''-DTPA(B-355)

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
p-SCN-Bn-CHX-A”-DTPA
1mg
$ 45.00

Total 7 raw suppliers

Chemical Property of CHX-A''-DTPA(B-355)

Chemical Property:

PSA：240.67000
LogP:0.97220

Purity/Quality:

98% ^*data from raw suppliers

p-SCN-Bn-CHX-A”-DTPA ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses p-SCN-Bn-CHX-A”-DTPA is a novel bifunctional maleimido CHX-A'''' chelator for conjugation to thiol-containing biomolecules such as trastuzumab and binding to ovarian cancer cells.

Technology Process of CHX-A''-DTPA(B-355)

There total 36 articles about CHX-A''-DTPA(B-355) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: {[(1R,2R)-2-(Bis-tert-butoxycarbonylmethyl-amino)-cyclohexyl]-[(R)-2-(bis-tert-butoxycarbonylmethyl-amino)-3-(4-nitro-phenyl)-propyl]-amino}-acetic acid tert-butyl ester

: 157380-45-5
{[(1R,2R)-2-(Bis-carboxymethyl-amino)-cyclohexyl]-[(R)-2-(bis-carboxymethyl-amino)-3-(4-isothiocyanato-phenyl)-propyl]-amino}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: TFA

2: H₂, Na₂CO₃ / 10percent Pd/C / H₂O

3: H₂O; CHCl₃ / 2 h

With hydrogen; sodium carbonate; trifluoroacetic acid; palladium on activated charcoal; In chloroform; water;
DOI:10.1016/S0968-0896(97)00130-2

Reference yield:

: 290836-21-4
{[(1S,2S)-2-(Bis-tert-butoxycarbonylmethyl-amino)-cyclohexyl]-[(S)-2-(bis-tert-butoxycarbonylmethyl-amino)-3-(4-nitro-phenyl)-propyl]-amino}-acetic acid tert-butyl ester

: 157380-45-5
{[(1S,2S)-2-(Bis-carboxymethyl-amino)-cyclohexyl]-[(S)-2-(bis-carboxymethyl-amino)-3-(4-isothiocyanato-phenyl)-propyl]-amino}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: TFA

2: H₂, Na₂CO₃ / 10percent Pd/C / H₂O

3: H₂O; CHCl₃ / 2 h

With hydrogen; sodium carbonate; trifluoroacetic acid; palladium on activated charcoal; In chloroform; water;
DOI:10.1016/S0968-0896(97)00130-2

Reference yield:

: 880644-82-6
N-[(R)-2-amino-3-(p-nitrophenyl)propyl]-trans-(S,S)-cyclohexane-1,2-diamine-N,N,N',N'',N''-penta-tert-butyl acetate

: 157380-45-5
{[(1S,2S)-2-(Bis-carboxymethyl-amino)-cyclohexyl]-[(R)-2-(bis-carboxymethyl-amino)-3-(4-isothiocyanato-phenyl)-propyl]-amino}-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: TFA

2: H₂, Na₂CO₃ / 10percent Pd/C / H₂O

3: H₂O; CHCl₃ / 2 h

With hydrogen; sodium carbonate; trifluoroacetic acid; palladium on activated charcoal; In chloroform; water;
DOI:10.1016/S0968-0896(97)00130-2