Spiro[2.5]octan-6-one

Base Information

Chemical Name:Spiro[2.5]octan-6-one
CAS No.:15811-21-9
Molecular Formula:C8H12O
Molecular Weight:124.183
Hs Code.:2914299000
European Community (EC) Number:822-465-6
DSSTox Substance ID:DTXSID40598451
Nikkaji Number:J1.505.285F
Wikidata:Q82494213
Mol file:15811-21-9.mol

Synonyms:Spiro[2.5]octan-6-one;15811-21-9;MFCD09868097;Spiro [2.5]octan-6-one;Spiro-[2.5]octan-6-one;SCHEMBL307414;DTXSID40598451;PXIGSUWVCSOFMF-UHFFFAOYSA-N;AKOS006314211;AS-39575;SY105833;DB-064201;CS-0038018;EN300-114094;A850086;J-524288;F8888-2702;Z1198235438

Suppliers and Price of Spiro[2.5]octan-6-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
spiro[2.5]octan-6-one
2.5mg
$ 45.00

Crysdot
Spiro[2.5]octan-6-one 95+%
1g
$ 675.00

Chemenu
spiro[2.5]octan-6-one 95%
1g
$ 632.00

Alichem
Spiro[2.5]octan-6-one
1g
$ 905.84

Alichem
Spiro[2.5]octan-6-one
250mg
$ 351.48

AK Scientific
Spiro[2.5]octan-6-one
5g
$ 4561.00

Total 17 raw suppliers

Chemical Property of Spiro[2.5]octan-6-one

Chemical Property:

Boiling Point:194.2±8.0 °C(Predicted)
PSA：17.07000
Density:1.02±0.1 g/cm3(Predicted)
LogP:1.90970
XLogP3:1.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:0
Exact Mass:124.088815002
Heavy Atom Count:9
Complexity:133

Purity/Quality:

98% ^*data from raw suppliers

spiro[2.5]octan-6-one ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC2(CCC1=O)CC2
Uses Spiro[2.5]octan-6-one can be used as P2X3 inhibitors to treat P2X3 receptor dysfunction diseases.

Technology Process of Spiro[2.5]octan-6-one

There total 8 articles about Spiro[2.5]octan-6-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 185-65-9
spiro[2.5]octane

: 15811-21-9
spiro[2.5]octan-6-one

: 25308-67-2
spiro[2.5]octan-5-one

: 2205-98-3
spiro[2.5]octan-4-one

Guidance literature:: With methyltrifluoromethyldioxirane; In dichloromethane; at 0 ℃; for 0.583333h;
DOI:10.1021/jo034768o

Reference yield: 87.0%

: 52875-47-5
7,10-dioxadispiro[2.2.4⁶.2³]dodecane

: 15811-21-9
spiro[2.5]octan-6-one

Guidance literature:: With water; trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield: 48.0%

: 51656-90-7
8-methylene-1,4-dioxaspiro[4.5]decane

: 75-11-6
diiodomethane

: 15811-21-9
spiro[2.5]octan-6-one

Guidance literature:: 8-methylene-1,4-dioxaspiro[4.5]decane; diiodomethane; With copper; zinc; In diethyl ether; for 29h; Heating;

With hydrogenchloride; at 20 ℃; for 1h; Further stages.;
DOI:10.1021/jo001292p