6-Methyl-2,3-diphenylquinoxaline

Base Information

• Chemical Name: 6-Methyl-2,3-diphenylquinoxaline
• CAS No.: 16107-85-0
• Molecular Formula: C21H16N2
• Molecular Weight: 296.371
• DSSTox Substance ID: DTXSID60364372
• Nikkaji Number: J1.048.199F
• Wikidata: Q82148304
• ChEMBL ID: CHEMBL1407275
• Mol file: 16107-85-0.mol

Synonyms:6-methyl-2,3-diphenylquinoxaline;16107-85-0;6-Methyl-2,3-diphenyl-quinoxaline;CDS1_003390;ChemDiv1_026686;MLS000712674;DivK1c_004430;SCHEMBL1104817;CHEMBL1407275;HMS662M22;DTXSID60364372;2,3-Diphenyl-6-methylquinoxaline;HMS2697E22;AKOS000536467;SMR000282441;EU-0027023;SR-01000554162;SR-01000554162-1;Z56788788

Chemical Property of 6-Methyl-2,3-diphenylquinoxaline

Chemical Property:

• PSA: 25.78000
• LogP: 5.27220
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 296.131348519
• Heavy Atom Count: 23
• Complexity: 370

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC1=CC2=C(C=C1)N=C(C(=N2)C3=CC=CC=C3)C4=CC=CC=C4

Technology Process of 6-Methyl-2,3-diphenylquinoxaline

There total 28 articles about 6-Methyl-2,3-diphenylquinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-methyl-1,2-diaminobenzene (496-72-0) + benzil (134-81-6) → 2,3-diphenyl-6-methylquinoxaline (16107-85-0)

Guidance literature:

at 100 ℃; for 0.25h;

DOI:10.1002/1099-0690(200204)2002:8<1368::AID-EJOC1368>3.0.CO;2-6

Reference yield: 97.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + 4-methyl-1,2-diaminobenzene (496-72-0) → 2,3-diphenyl-6-methylquinoxaline (16107-85-0)

Guidance literature:

With [P₄-VP]-PdNPs; In N,N-dimethyl-formamide; at 120 ℃; for 0.0216667h; Reflux;

DOI:10.1007/s13738-018-1290-6

Reference yield: 93.0%

phenyl benzyl ketone (451-40-1) + 4-methyl-1,2-diaminobenzene (496-72-0) → 2,3-diphenyl-6-methylquinoxaline (16107-85-0)

Guidance literature:

With oxygen; triethylamine; In toluene; at 90 ℃; for 12h; under 760.051 Torr;

DOI:10.1016/j.tet.2012.03.020

upstream raw materials:

1,2-diphenyl-2-(phenylamino)ethanone

4-methyl-1,2-diaminobenzene

benzil

4,5-Dihydroxy-4,5-diphenylimidazolidin-2-on

Downstream raw materials:

6-bromomethyl-2,3-diphenylquinoxaline

C₂₅H₂₀N₂O₄

(2-(7-methyl-3-phenylquinoxalin-2-yl)phenyl)(phenyl)methanone

(2-(6-methyl-3-phenylquinoxalin-2-yl)phenyl)(phenyl)methanone