Benzyloxycyclohexane

Base Information

• Chemical Name: Benzyloxycyclohexane
• CAS No.: 16224-09-2
• Molecular Formula: C13H18O
• Molecular Weight: 190.285
• Hs Code.: 2909309090
• Mol file: 16224-09-2.mol

Synonyms:Ether,benzyl cyclohexyl;[(Cyclohexyloxy)methyl]benzene;Benzyl-cyclohexyl-aether;Benzyloxycyclohexane;benzyl cyclohexyl ether;cyclohexyl benzyl ether;Benzene,[(cyclohexyloxy)methyl];

Chemical Property of Benzyloxycyclohexane

Chemical Property:

• Vapor Pressure: 0.0101mmHg at 25°C
• Boiling Point: 272.6oC at 760 mmHg
• Flash Point: 113.1oC
• PSA: 9.23000
• Density: 0.98g/cm3
• LogP: 3.53590

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzyloxycyclohexane

There total 55 articles about Benzyloxycyclohexane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

benzyloxy-trimethylsilane (14642-79-6) + cyclohexanone (108-94-1,11119-77-0,9003-41-2,9075-99-4) → benzyl cyclohexyl ether (16224-09-2)

Guidance literature:

With triethylsilane; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 - -30 ℃;

DOI:10.1016/S0040-4039(00)73357-0

Reference yield: 100.0%

benzaldehyde (100-52-7) + cyclohexyloxy-dimethyl-silane → benzyl cyclohexyl ether (16224-09-2)

Guidance literature:

With trimethylsilyl iodide; In dichloromethane; at 0 - 20 ℃; for 2h;

DOI:10.1055/s-2002-19779

Reference yield: 99.0%

trimethylsilyl cyclohexyl ether (13871-89-1) + benzaldehyde (100-52-7) → benzyl cyclohexyl ether (16224-09-2)

Guidance literature:

With triethylsilane; trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 - -30 ℃;

DOI:10.1016/S0040-4039(00)73357-0

upstream raw materials:

benzyl chloride

cyclohexanol

benzyl alcohol

phenyldiazomethane

Downstream raw materials:

cyclohexylphenylmethanol

benzoic acid cyclohexyl ester

benzyl chloride

benzil

Refernces

• 1、 Pelosi, Azzurra,Lanari, Daniela,Temperini, Andrea,Curini, Massimo,Rosati, Ornelio. "Reductive Etherification of Aldehydes and Ketones with Alcohols and Triethylsilane Catalysed by Yb(OTf)3: an Efficient One-Pot Benzylation of Alcohols". supporting information. p. 4527 - 4539. Retrieved 2019/08/26.
• 2、 Bayguzina,Gimaletdinova,Khusnutdinov. "Synthesis of Benzyl Alkyl Ethers by Intermolecular Dehydration of Benzyl Alcohol with Aliphatic Alcohols under the Effect of Copper Containing Catalysts". . p. 1148 - 1155. Retrieved 2018/10/24.