(Cyclohexyloxy)trimethylsilane

Base Information

• Chemical Name: (Cyclohexyloxy)trimethylsilane
• CAS No.: 13871-89-1
• Molecular Formula: C9H20OSi
• Molecular Weight: 172.343
• Hs Code.: 2931900090
• NSC Number: 96833
• UNII: D2GRT3EQH3
• DSSTox Substance ID: DTXSID70294499
• Nikkaji Number: J44.186D
• Wikidata: Q82033841
• Mol file: 13871-89-1.mol

Synonyms:(Cyclohexyloxy)trimethylsilane;Silane, (cyclohexyloxy)trimethyl-;13871-89-1;cyclohexyloxy(trimethyl)silane;D2GRT3EQH3;Trimethylcyclohexyloxysilane;NSC-96833;(Trimethylsilyloxy)cyclohexane;1-(Trimethylsiloxy)cyclohexane;Cyclohexanol trimethylsilyl ether;UNII-D2GRT3EQH3;Cyclohexanol, TMS derivative;cyclohexyloxy-trimethyl-silane;Trimethyl(cyclohexyloxy)silane;((Trimethylsilyl)oxy)cyclohexane;Cyclohexane, ((trimethylsilyl)oxy)-;[(Trimethylsilyl)oxy]cyclohexane;Cyclohexane, [(trimethylsilyl)oxy]-;NSC96833;Trimethylsiloxycyclohexane;Trimethylsilyloxycyclohexane;Trimethyl-cyclohexyloxy-silane;Cyclohexanol, O-trimethylsilyl;SCHEMBL301584;1-(trimethylsilyloxy)cyclohexane;DTXSID70294499

Chemical Property of (Cyclohexyloxy)trimethylsilane

Chemical Property:

• Vapor Pressure: 1.71mmHg at 25°C
• Boiling Point: 173.3°Cat760mmHg
• Flash Point: 49.1°C
• PSA: 9.23000
• Density: 0.85g/cm³
• LogP: 3.17060
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 172.128341792
• Heavy Atom Count: 11
• Complexity: 111

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)OC1CCCCC1

Technology Process of (Cyclohexyloxy)trimethylsilane

There total 34 articles about (Cyclohexyloxy)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,1,1,3,3,3-hexamethyl-disilazane (999-97-3) + cyclohexanol (108-93-0) → trimethylsilyl cyclohexyl ether (13871-89-1)

Guidance literature:

1,3-dibromo-5,5-dimethylimidazolidine-2,4-dione; In dichloromethane; at 20 ℃; for 9.96667h;

DOI:10.1002/jccs.200700068

Reference yield: 97.0%

chloro-trimethyl-silane (75-77-4) + cyclohexanol (108-93-0) → trimethylsilyl cyclohexyl ether (13871-89-1)

Guidance literature:

With iron perchlorate hexahydrate; In dichloromethane; at 20 ℃; for 1.33333h;

DOI:10.1080/10426500802336606

Reference yield: 97.0%

1,1,1,2,2,2-hexamethyldisilane (1450-14-2) + cyclohexanol (108-93-0) → trimethylsilyl cyclohexyl ether (13871-89-1)

Guidance literature:

With lanthanum(III) nitrate hexahydrate; In acetonitrile; at 20 ℃;

DOI:10.1080/10426500802509616

upstream raw materials:

Hexamethyldisiloxane

cyclohexanol

trimethylsilyl iodide

2-methoxycyclohexane

Downstream raw materials:

C₁₂H₁₆FO₂P

C₁₂H₁₆F₃OP

fluorocyclohexane

Cyclohexyl iodide

Refernces

• 1、 Khazaei, Ardeshir,Rostami, Amin,Rahmati, Sadegh,Mahboubifar, Marjan. "N,N′-dibromo-N,N′-1,2-ethanediylbis (benzene sulfonamide) as a novel N-bromo reagent-catalyzed trimethylsilylation of alcohols and phenol with hexamethyldisilazane in both solution and solvent-free conditions". . p. 537 - 544. Retrieved 2007.
• 2、 Dey, Rupa Rani,Dhar, Siddhartha Sankar. "Synthesis and characterization of 2-carboxyethyltriphenyl phosphonium tribromide and its application as catalyst in silylation of alcohols and thiols under solvent-free condition". . p. 2355 - 2363. Retrieved 2014.
• 3、 Jadhav, Vrushali H.,Kumar, K. S. Ajish,Chaudhari, Vinod D.,Dhavale, Dilip D.. "Facile method for trimethylsilylation of alcohols using hexamethyldisilazane and ammonium thiocyanate under neutral conditions". . p. 1363 - 1370. Retrieved 2007.
• 4、 Rahmatpour, Ali,Vakili, Ali,Azizian, Setare. "Polystyrene-gallium trichloride complex: A mild, highly efficient, and recyclable polymeric lewis acid catalyst for chemoselective silylation of alcohols and phenols with hexamethyldisilazane". . p. 443 - 451. Retrieved 2013.
• 5、 Chen, Jyun-Siao,Huang, Po-Hsun,Hsieh, Ya-Chi,Liu, Jen-Wei,Hsu, Hsiao-Lin,Zhang, Kai-Min,Wu, Ren-Tsung,Chang, Ting-Shuo,Liu, Yu-Hao,Wu, Hsin-Ru,Luo, Shun-Yuan. "Trimethylsilyl Esters as Novel Dual-Purpose Protecting Reagents". supporting information. p. 754 - 762. Retrieved 2021/12/02.
• 6、 Bordet, Alexis,Emondts, Meike,Kacem, Souha,Leitner, Walter. "Selective hydrogenation of fluorinated arenes using rhodium nanoparticles on molecularly modified silica". . p. 8120 - 8126. Retrieved 2020/12/28.