3-(2-Methyl-1,3-dioxolan-2-yl)oxolan-2-one

Base Information

• Chemical Name: 3-(2-Methyl-1,3-dioxolan-2-yl)oxolan-2-one
• CAS No.: 31536-34-2
• Molecular Formula: C₈H₁₂O₄
• Molecular Weight: 172.181
• Hs Code.: 2932999099
• European Community (EC) Number: 608-632-4
• NSC Number: 134772
• DSSTox Substance ID: DTXSID80300095
• Mol file: 31536-34-2.mol

Synonyms:31536-34-2;3-(2-methyl-1,3-dioxolan-2-yl)oxolan-2-one;3-(2-methyl-1,3-dioxolan-2-yl)tetrahydrofuran-2-one;NSC 134772;NSC134772;3-(2-methyl-1,3-dioxolan-2-yl)dihydrofuran-2(3h)-one;SCHEMBL7529118;DTXSID80300095;NSC-134772

Chemical Property of 3-(2-Methyl-1,3-dioxolan-2-yl)oxolan-2-one

Chemical Property:

• Vapor Pressure: 0.000936mmHg at 25°C
• Boiling Point: 303.3°C at 760 mmHg
• Flash Point: 134.9°C
• PSA: 44.76000
• Density: 1.237g/cm³
• LogP: 0.31250
• XLogP3: 0
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 172.07355886
• Heavy Atom Count: 12
• Complexity: 195

Purity/Quality:

99% ^*data from raw suppliers

3-(2-METHYL-1,3-DIOXOLAN-2-YL)TETRAHYDROFURAN-2-ONE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1(OCCO1)C2CCOC2=O

Technology Process of 3-(2-Methyl-1,3-dioxolan-2-yl)oxolan-2-one

There total 2 articles about 3-(2-Methyl-1,3-dioxolan-2-yl)oxolan-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

3-acetyl-2-oxo-4,5-dihydrofuran (517-23-7,594837-91-9,98634-97-0,313643-49-1) + ethylene glycol (107-21-1) → 2-oxo-3(1',1'-ethylenedioxy) ethyltetrahydrofurane (31536-34-2)

Guidance literature:

With toluene-4-sulfonic acid; In benzene; Heating;

DOI:10.1007/BF01160965

Reference yield:

→ 2-oxo-3(1',1'-ethylenedioxy) ethyltetrahydrofurane (31536-34-2)

Guidance literature:

Butyrolacton IV, Ethylenglycal;

DOI:10.1039/j39710000999

Reference yield: 43.3%

2-oxo-3(1',1'-ethylenedioxy) ethyltetrahydrofurane (31536-34-2) + 4-methoxy-benzylamine (2393-23-9) → N-(p-methoxybenzyl)amide of α-(1',1'-ethylenedioxy)-ethyl-γ-hydroxybutyric acid (128746-85-0)

Guidance literature:

In toluene; for 12h; Heating;

DOI:10.1007/BF01160965

upstream raw materials:

3-acetyl-2-oxo-4,5-dihydrofuran

ethylene glycol

Downstream raw materials:

N-(2-phenylethyl)amide of α-(1',1'-ethylenedioxy)-ethyl-γ-hydroxybutyric acid

N-(p-methoxybenzyl)amide of α-(1',1'-ethylenedioxy)-ethyl-γ-hydroxybutyric acid

4-Hydroxy-N-(4-methyl-benzyl)-2-(2-methyl-[1,3]dioxolan-2-yl)-butyramide

N-(2-phenylethyl)amide of α-(1,1-ethylenedioxy)-ethyl-γ-chlorobutyric acid