2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid

Base Information

Chemical Name:2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid
CAS No.:174422-17-4
Molecular Formula:C15H12N2O3
Molecular Weight:268.272
Hs Code.:
DSSTox Substance ID:DTXSID20354850
Wikidata:Q82133322
ChEMBL ID:CHEMBL1672856
Mol file:174422-17-4.mol

Synonyms:174422-17-4;2-(4-METHOXYPHENYL)-1H-BENZO[D]IMIDAZOLE-5-CARBOXYLIC ACID;2-(4-methoxyphenyl)-3H-benzimidazole-5-carboxylic acid;1H-Benzimidazole-6-carboxylic acid, 2-(4-methoxyphenyl)-;SCHEMBL1662758;CHEMBL1672856;DTXSID20354850;AKOS009356372;2-(4-Methoxyphenyl)-1H-benzimidazole-6-carboxylic acid

Suppliers and Price of 2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID 95.00%
5MG
$ 497.48

Total 2 raw suppliers

Chemical Property of 2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid

Chemical Property:

PSA：75.21000
LogP:2.93670
XLogP3:2.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:268.08479225
Heavy Atom Count:20
Complexity:355

Purity/Quality:

99% ^*data from raw suppliers

2-(4-METHOXYPHENYL)-1H-BENZIMIDAZOLE-5-CARBOXYLIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C2=NC3=C(N2)C=C(C=C3)C(=O)O

Technology Process of 2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid

There total 9 articles about 2-(4-Methoxyphenyl)-1H-benzo[D]imidazole-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 123-11-5
4-methoxy-benzaldehyde

: 1588-83-6
4-amino-3-nitrobenzoic acid

: 174422-17-4
2-(4-methoxyphenyl)-1H-benzo[d]imidazole-5-carboxylic acid

Guidance literature:: With sodium dithionite; In ethanol; at 70 ℃; for 5h;
DOI:10.1055/s-2004-834926

Reference yield: 78.0%

: 123-11-5
4-methoxy-benzaldehyde

: 619-05-6
3,4-diaminobenzoic acid

: 174422-17-4
2-(4-methoxyphenyl)-1H-benzo[d]imidazole-5-carboxylic acid

Guidance literature:: With tetrabutoxytitanium; bis(acetylacetonate)oxovanadium; oxygen; magnesium sulfate; In tetrahydrofuran; at 0 - 20 ℃; chemoselective reaction;
DOI:10.1021/jo901458k

Reference yield: 75.0%

: 135-02-4
ortho-anisaldehyde

: 619-05-6
3,4-diaminobenzoic acid

: 174422-17-4
2-(4-methoxyphenyl)-1H-benzo[d]imidazole-5-carboxylic acid

Guidance literature:: With bis(acetylacetonate)oxovanadium; cetyltrimethylammonim bromide; copper(II) bis(trifluoromethanesulfonate); In water; at 20 ℃; for 18h; chemoselective reaction; Green chemistry;
DOI:10.13005/ojc/360413