N-Methyl-N-trimethylsilylaniline

Base Information

• Chemical Name: N-Methyl-N-trimethylsilylaniline
• CAS No.: 17890-34-5
• Molecular Formula: C10H17NSi
• Molecular Weight: 179.337
• DSSTox Substance ID: DTXSID10497407
• Nikkaji Number: J46.967J
• Wikidata: Q63409541
• Mol file: 17890-34-5.mol

Synonyms:N-Methyl-N-trimethylsilylaniline;17890-34-5;N,1,1,1-Tetramethyl-N-phenylsilanamine;SCHEMBL2670162;N-trimethylsilyl-N-methylaniline;DTXSID10497407;N-(Trimethylsilyl)-N-methylaniline;N-Methyl-N-(trimethylsilyl)aniline;Silylamine, N,1,1,1-tetramethyl-N-phenyl-;Q63409541

Chemical Property of N-Methyl-N-trimethylsilylaniline

Chemical Property:

• Boiling Point: 110-112 °C(Press: 53 Torr)
• PSA: 3.24000
• Density: 0.914±0.06 g/cm3(Predicted)
• LogP: 2.95770
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 179.113026081
• Heavy Atom Count: 12
• Complexity: 133

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C1=CC=CC=C1)[Si](C)(C)C

Technology Process of N-Methyl-N-trimethylsilylaniline

There total 3 articles about N-Methyl-N-trimethylsilylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

chloro-trimethyl-silane (75-77-4) + N-methylaniline (100-61-8) → N-(trimethylsilyl)phenyl(methyl)amine (17890-34-5)

Guidance literature:

N-methylaniline; With n-butyllithium; In diethyl ether; hexane; at -78 - -60 ℃; for 1h; Inert atmosphere;

chloro-trimethyl-silane; In diethyl ether; hexane; at -70 - 20 ℃; Inert atmosphere;

Reference yield: 60.0%

N,O-Bis(trimethylsilyl)trifluoroacetamide (25561-30-2) + N-methylaniline (100-61-8) → N-(trimethylsilyl)phenyl(methyl)amine (17890-34-5)

Guidance literature:

In acetonitrile; at 105 ℃; for 24h;

DOI:10.1021/jo201329n

Reference yield:

→ N-(trimethylsilyl)phenyl(methyl)amine (17890-34-5)

Guidance literature:

aus Verb.I (Thermolyse);

DOI:10.1016/S0022-328X(00)93367-9

upstream raw materials:

chloro-trimethyl-silane

N-methylaniline

N,O-Bis(trimethylsilyl)trifluoroacetamide

Downstream raw materials:

N-Methyl-N'-trimethylsilyl-N,N'-diphenyl-harnstoff

N_.N'-Dimethyl-N-phenyl-N'-trimethylsilyl-harnstoff

N-methyl-N-phenylthiocarbamoyl chloride

S-trimethylsilyl O-i-propyldithiocarbonate