2-Chloro-4-cyclohexylphenol

Base Information

• Chemical Name: 2-Chloro-4-cyclohexylphenol
• CAS No.: 3964-61-2
• Molecular Formula: C₁₂H₁₅ClO
• Molecular Weight: 210.704
• Mol file: 3964-61-2.mol

Synonyms:2-Chloro-4-cyclohexylphenol;NSC 74802

Chemical Property of 2-Chloro-4-cyclohexylphenol

Chemical Property:

• Vapor Pressure: 0.00033mmHg at 25°C
• Melting Point: 40.5°C
• Refractive Index: 1.5300 (estimate)
• Boiling Point: 310.4°C at 760 mmHg
• Flash Point: 141.5°C
• PSA: 20.23000
• Density: 1.163g/cm³
• LogP: 4.09330

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Chloro-4-cyclohexylphenol

There total 10 articles about 2-Chloro-4-cyclohexylphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-cyclohexylphenol (1131-60-8) → 2-chloro-4-cyclohexyl-phenol (3964-61-2)

Guidance literature:

With tetrachloromethane; at 70 ℃; Einleiten von Chlor;

Reference yield:

2-monochlorophenol (95-57-8) + cyclohexene (110-83-8) → 2-chloro-4-cyclohexyl-phenol (3964-61-2) + 2-chloro-6-cyclohexyl-phenol (57883-04-2)

Guidance literature:

With boron trifluoride; at 30 - 35 ℃;

Reference yield:

cyclohexyl chloride (542-18-7) + 2-monochlorophenol (95-57-8) → 2-chloro-4-cyclohexyl-phenol (3964-61-2) + 2-chloro-6-cyclohexyl-phenol (57883-04-2)

Guidance literature:

iron(III) chloride; at 135 - 145 ℃; for 0.333333h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

upstream raw materials:

2-monochlorophenol

cyclohexene

p-cyclohexylphenol

cyclohexyl chloride

Downstream raw materials:

2-Aminomethyl-6-chloro-4-cyclohexyl-phenol; hydrochloride