Trimethylsilyl diethylcarbamate

Base Information

• Chemical Name: Trimethylsilyl diethylcarbamate
• CAS No.: 18279-61-3
• Molecular Formula: C8H19NO2Si
• Molecular Weight: 189.33
• DSSTox Substance ID: DTXSID90498851
• Nikkaji Number: J2.593.973E
• Wikidata: Q82349171
• Mol file: 18279-61-3.mol

Synonyms:Trimethylsilyl diethylcarbamate;18279-61-3;SCHEMBL6674015;DTXSID90498851;MKFOKGIKAMJXHY-UHFFFAOYSA-N;N,N-Diethyl(trimethylsilyl)carbamate;N,N-Diethyl-(trimethylsilyl)-carbamate

Chemical Property of Trimethylsilyl diethylcarbamate

Chemical Property:

• Vapor Pressure: 1.29mmHg at 25°C
• Boiling Point: 173.1oC at 760 mmHg
• Flash Point: 58.5oC
• PSA: 29.54000
• Density: 0.914g/cm3
• LogP: 2.29970
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 189.118505383
• Heavy Atom Count: 12
• Complexity: 150

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C(=O)O[Si](C)(C)C

Technology Process of Trimethylsilyl diethylcarbamate

There total 3 articles about Trimethylsilyl diethylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + diethylamine (109-89-7) + 1-(Trimethylsilyl)imidazole (18156-74-6) → 1H-imidazole (288-32-4) + trimethylsilyl diethylcarbamate (18279-61-3)

Guidance literature:

at 45 - 50 ℃; for 6h; Inert atmosphere;

DOI:10.1134/S1070363213070116

Reference yield:

carbon dioxide (124-38-9,18923-20-1) + 3,5-dimethyl-1-(trimethylsilyl)-1H-pyrazole (18290-96-5) + diethylamine (109-89-7) → 3,5-dimethyl-1H-pyrazole (67-51-6) + trimethylsilyl diethylcarbamate (18279-61-3)

Guidance literature:

at 45 - 50 ℃; for 6h; Inert atmosphere;

DOI:10.1134/S1070363213070116

Reference yield:

trimethylsilyl carbamate (58078-34-5) + diethylamine (109-89-7) → N,N-diethylurea (634-95-7) + trimethylsilyl diethylcarbamate (18279-61-3)

Guidance literature:

at 40 - 50 ℃; for 1h; Yield given;

upstream raw materials:

trimethylsilyl carbamate

diethylamine

carbon dioxide

1-(Trimethylsilyl)imidazole

Downstream raw materials:

N-(Trimethylsilyl)-L-Phe-t-butyl-ester

N-(Trimethylsiloxycarbonyl)-L-Phe-t-butyl-ester

N,N'-bis-<β-(trimethylsiloxy)>ethylcarbodiimide

diethylamine