3-Methyl-1-butynyltrimethylsilane

Base Information

• Chemical Name: 3-Methyl-1-butynyltrimethylsilane
• CAS No.: 18388-07-3
• Molecular Formula: C8H16Si
• Molecular Weight: 140.301
• Mol file: 18388-07-3.mol

Synonyms:3-methyl-1-trimethylsilyl-1-butyne;trimethyl-(3-methyl-but-1-ynyl)-silane;3-methyl-1-(trimethylsilyl)but-1-yne;2.2.5-Trimethyl-2-sila-3-hexin;1-Trimethylsilyl-3-methyl-butin-(1);3-Methyl-1-(trimethylsilyl)-1-butyne;

Chemical Property of 3-Methyl-1-butynyltrimethylsilane

Chemical Property:

• Boiling Point: 124.9±9.0 °C(Predicted)
• PSA: 0.00000
• Density: 0.779±0.06 g/cm3(Predicted)
• LogP: 2.52320

Purity/Quality:

99% ^*data from raw suppliers

Trimethyl(3-methyl-1-butyn-1-yl)silane ≥95% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-1-butynyltrimethylsilane

There total 13 articles about 3-Methyl-1-butynyltrimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

chloro-trimethyl-silane (75-77-4) + 3-methyl-but-1-yne (598-23-2) → trimethyl(3-methylbut-1-yn-1-yl)silane (18388-07-3)

Guidance literature:

3-methyl-but-1-yne; With n-butyllithium; In tetrahydrofuran; hexane; at -78 ℃; for 0.5h; Inert atmosphere;

chloro-trimethyl-silane; In tetrahydrofuran; hexane; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1021/jacs.7b06286

Reference yield: 33.0%

4,8-Diisopropyl-2,2,6,6-tetramethyl-3,7-bis(trimethylsilyl)-1,5-dioxa-2,6-disila-3,7-cyclooctadiene (118107-32-7) → trimethyl(3-methylbut-1-yn-1-yl)silane (18388-07-3) + 6-Isopropyl-2,2,4,4-tetramethyl-5-(trimethylsilyl)-1,3-dioxa-2,4-disila-5-cyclohexene (118096-56-3)

Guidance literature:

In diethyl ether; at 100 ℃; for 0.5h;

Reference yield: 10.0%

(3-chloro-3-methylbut-1-yn-1-yl)trimethylsilane (18387-63-8) → trimethyl(3-methylbut-1-yn-1-yl)silane (18388-07-3) + 1-(trimethylsilyl)-3-methyl-1,2-butadiene (65108-51-2) + 1,6-bis(trimethylsilyl)-3,3,4,4-tetramethylhexa-1,5-diyne (81358-52-3)

Guidance literature:

With magnesium; In tetrahydrofuran;

DOI:10.1039/c39810001094

upstream raw materials:

chloro-trimethyl-silane

1-lithio-3-methyl-1-butyne

3-methyl-but-1-yne

3-methyl-1,3-bis(trimethylsilyl)-1-butyne

Downstream raw materials:

3-methyl-1,3-bis(trimethylsilyl)-1-butyne

3-methyl-1,1-bis(trimethylsilyl)-1,2-butadiene

1,3,5-triisopropyl benzene

Refernces

• 1、 Wang, Jiaxi,Gurevich, Ylia,Botoshansky, Mark,Eisen, Moris S.. "Unique σ-bond metathesis of silylalkynes promoted by an ansa-dimethylsilyl and oxo-bridged uranium metallocene". . p. 9350 - 9351. Retrieved 2007/10/03.
• 2、 Duhamel, Lucette. "A new route to α,β-unsaturated aldehydes using the condensation of trimethylsilyl β-trimethylsilyl enol ethers with aldehydes". . p. 7745 - 7748. Retrieved 2007/10/02.