N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine

Base Information

• Chemical Name: N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine
• CAS No.: 18677-85-5
• Molecular Formula: C10H23N
• Molecular Weight: 157.299
• DSSTox Substance ID: DTXSID30498638
• Wikidata: Q82348825
• Mol file: 18677-85-5.mol

Synonyms:N,N-diisobutylethylamine;18677-85-5;diisobutylethylamine;ethyldiisobutylamine;N,N-diisobutyl ethylamine;SCHEMBL35704;N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine;DTXSID30498638;XQQLJWFNDMEBHP-UHFFFAOYSA-N

Chemical Property of N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine

Chemical Property:

• PSA: 3.24000
• LogP: 2.62030
• XLogP3: 3.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 5
• Exact Mass: 157.183049738
• Heavy Atom Count: 11
• Complexity: 76.9

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC(C)C)CC(C)C

Technology Process of N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine

There total 1 articles about N-Ethyl-2-methyl-N-(2-methylpropyl)propan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Isobutyronitrile (78-82-0) + ethylamine (75-04-7,85404-22-4) → diisobutylamine (110-96-3) + N-ethylisobutylamine (13205-60-2) + N-ethylbis(isobutyl)amine (18677-85-5)

Guidance literature:

With hydrogen; palladium;

DOI:10.1016/j.tetlet.2012.06.044

Reference yield: 69.0%

iodobenzene (591-50-4) + N-ethylbis(isobutyl)amine (18677-85-5) + carbon monoxide (201230-82-2) + 2-methyl-1-phenylbuta-2,3-dien-1-ol (78808-42-1) → N,N-diisopropyl-2-(4-methyl-2,5-diphenylfuran-3-yl)acetamide

Guidance literature:

With palladium dichloride; Trimethylacetic acid; In acetonitrile; at 80 ℃; for 8h; regioselective reaction;

DOI:10.1021/acs.joc.8b01753

Reference yield: 65.0%

2-ethyl-1-(4-methylphenyl)buta-2,3-dien-1-ol (865762-71-6) + iodobenzene (591-50-4) + N-ethylbis(isobutyl)amine (18677-85-5) + carbon monoxide (201230-82-2) → 2-(4-ethyl-2-phenyl-5-(p-tolyl)furan-3-yl)-N,N-diisopropylacetamide

Guidance literature:

With palladium dichloride; Trimethylacetic acid; In acetonitrile; at 80 ℃; for 8h; regioselective reaction;

DOI:10.1021/acs.joc.8b01753

upstream raw materials:

Isobutyronitrile

ethylamine