1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene

Base Information

Chemical Name:1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene
CAS No.:37629-90-6
Molecular Formula:C15H13NO3
Molecular Weight:255.273
Hs Code.:
DSSTox Substance ID:DTXSID701231033
Mol file:37629-90-6.mol

Synonyms:DTXSID701231033;1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene

Suppliers and Price of 1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene

Chemical Property:

Vapor Pressure:6.15E-06mmHg at 25°C
Boiling Point:390°C at 760 mmHg
Flash Point:164.7°C
Density:1.199g/cm³
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:255.08954328
Heavy Atom Count:19
Complexity:321

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC=C(C=C1)C=C(C2=CC=CC=C2)[N+](=O)[O-]
Isomeric SMILES:COC1=CC=C(C=C1)/C=C(\C2=CC=CC=C2)/[N+](=O)[O-]

Technology Process of 1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene

There total 10 articles about 1-Methoxy-4-[(1E)-2-nitro-2-phenylethenyl]benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 59019-40-8
1-[(1Z)-2-bromo-2-nitroethenyl]-4-methoxybenzene

: 98-80-6
phenylboronic acid

: 37629-90-6
(E)-2-(4'-methoxyphenyl)-1-nitro-1-phenylethene

Guidance literature:: With sodium hydrogencarbonate; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In ethanol; water; toluene; for 6h; Heating;
DOI:10.1016/j.tet.2007.09.012

Reference yield: 62.0%

: 622-42-4
1-nitro-1-phenylmethane

: 3910-55-2
N-(p-methoxybenzylidene)butylamine

: 37629-90-6
(E)-2-(4'-methoxyphenyl)-1-nitro-1-phenylethene

Guidance literature:: With acetic acid; In methanol; at 20 ℃; for 2.5h; Inert atmosphere;
DOI:10.1021/jo2013516

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 37629-90-6
(E)-2-(4'-methoxyphenyl)-1-nitro-1-phenylethene

Guidance literature:: Multi-step reaction with 3 steps

1: sodium hydroxide / methanol / 1 h / 5 °C / Inert atmosphere

2: pyridine; bromine / cyclohexane / Inert atmosphere; Reflux

3: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / tetrahydrofuran; water / 20 °C / Inert atmosphere; Reflux

With pyridine; tetrakis(triphenylphosphine) palladium⁽⁰⁾; bromine; sodium carbonate; sodium hydroxide; In tetrahydrofuran; methanol; cyclohexane; water; 1: Henry reaction / 3: Suzuki-Miyaura coupling;
DOI:10.1021/jo2013516