3-methoxy-9H-carbazole

Base Information

• Chemical Name: 3-methoxy-9H-carbazole
• CAS No.: 18992-85-3
• Molecular Formula: C13H11NO
• Molecular Weight: 197.236
• Hs Code.: 2933990090
• Mol file: 18992-85-3.mol

Synonyms:3-Methoxycarbazole;Carbazole,3-methoxy;3-Methoxycarbazol;9H-Carbazole,3-methoxy;

Chemical Property of 3-methoxy-9H-carbazole

Chemical Property:

• Vapor Pressure: 5.26E-06mmHg at 25°C
• PSA: 25.02000
• LogP: 3.32970

Purity/Quality:

98.5% ^*data from raw suppliers

3-methoxy-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-methoxy-9H-carbazole

There total 64 articles about 3-methoxy-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

6-Methoxy-1,2,3,4-tetrahydrocarbazole (13070-45-6) → 3-methoxycarbazole (18992-85-3)

Guidance literature:

With copper(II) choride dihydrate; In dimethyl sulfoxide; at 100 ℃; for 7h;

DOI:10.1016/j.tetlet.2018.01.061

Reference yield: 92.0%

methanol (67-56-1) + 3-bromo-9H-carbazole (1592-95-6) → 3-methoxycarbazole (18992-85-3)

Guidance literature:

With sodium methylate; copper(I) bromide; In ethyl acetate; at 80 ℃; for 16h; Inert atmosphere;

DOI:10.1002/chem.201201719

Reference yield: 87.0%

C14H13NO2 → 3-methoxycarbazole (18992-85-3)

Guidance literature:

With 2Rh⁽¹⁺⁾*2C₈H₁₂*2CF₃O₃S^(1-); 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1-methyl-pyrrolidin-2-one; at 190 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.tet.2015.04.058

upstream raw materials:

6-Methoxy-1,2,3,4-tetrahydrocarbazole

methanol

6-bromo-1,2,3,4-tetrahydro-9H-carbazole

4-[N-(4-methoxyphenyl)amino]benzaldehyde

Downstream raw materials:

3-hydroxy-9-methylcarbazole

4,4'-((2,3,5,6-tetramethyl-4-(6-methoxy-9-methyl-9H-carbazol-3-yl)phenyl) boranediyl)bis(2,3,5,6-tetramethylbenzonitrile)

3-methoxy-9-phenyl-9H-carbazole

Refernces

• 1、 Botman, Peter N. M.,Postma, Martijn,Fraanje, Jan,Goubitz, Kees,Schenk, Henk,Van Maarseveen, Jan H.,Hiemstra, Henk. "Synthesis and resolution of BICOL, a carbazole analogue of BINOL". . p. 1952 - 1955. Retrieved 2002.
• 2、 Steingruber, H. Sebastián,Mendioroz, Pamela,Volpe, María A.,Gerbino, Darío C.. "Convenient One-Pot Synthesis of 9 H -Carbazoles by Microwave Irradiation Employing a Green Palladium-Based Nanocatalyst". . p. 4048 - 4058. Retrieved 2021/08/03.
• 3、 Akiyama, Toshiki,Arisawa, Mitsuhiro,Haneoka, Hitoshi,Harada, Kazuo,Hasegawa, Jun-Ya,Honma, Tetsuo,Mashima, Kazushi,Sato, Yoshihiro,Shimoda, Shuhei,Shio, Yasunori,Suzuki, Takeyuki,Tamenori, Yusuke,Tsurugi, Hayato,Tsuruta, Kazuki,Wada, Yuki,Yamada, Makito. "Self-Assembled Multilayer Iron(0) Nanoparticle Catalyst for Ligand-Free Carbon-Carbon/Carbon-Nitrogen Bond-Forming Reactions". supporting information. p. 7244 - 7249. Retrieved 2020/10/12.