N-octadecylbenzamide

Base Information

• Chemical Name: N-octadecylbenzamide
• CAS No.: 19083-52-4
• Molecular Formula: C25H43NO
• Molecular Weight: 373.61500
• Hs Code.: 2924299090
• European Community (EC) Number: 633-775-4
• DSSTox Substance ID: DTXSID20404369
• Nikkaji Number: J39.364I
• Mol file: 19083-52-4.mol

Synonyms:N-octadecylbenzamide;19083-52-4;N-stearylbenzamide;SCHEMBL421014;DTXSID20404369;HWEOYOXBRATLKT-UHFFFAOYSA-N;AKOS024433212

Chemical Property of N-octadecylbenzamide

Chemical Property:

• PSA: 32.59000
• LogP: 8.25270
• XLogP3: 8.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 18
• Exact Mass: 373.334464995
• Heavy Atom Count: 27
• Complexity: 322

Purity/Quality:

99%, ^*data from raw suppliers

N-OCTADECYLBENZAMIDE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCCCCCCCCCCCCCNC(=O)C1=CC=CC=C1

Technology Process of N-octadecylbenzamide

There total 7 articles about N-octadecylbenzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

benzamide (55-21-0,27208-38-4) + 1-aminooctadecane (124-30-1) → N-octadecylbenzamide (19083-52-4)

Guidance literature:

With benzoic acid; In para-xylene; at 130 ℃; for 8h; Inert atmosphere; Schlenk technique;

DOI:10.1002/adsc.201400068

Reference yield: 35.0%

acetophenone (98-86-2) + 1-aminooctadecane (124-30-1) → N-octadecylbenzamide (19083-52-4)

Guidance literature:

With iodine; sodium hydroxide; In water; at 60 ℃; for 4h;

DOI:10.3184/174751911X13053065216840

Reference yield:

benzoyl chloride (98-88-4) + 1-aminooctadecane (124-30-1) → N-octadecylbenzamide (19083-52-4)

Guidance literature:

postcolumn derivatization in gas chromatography;

DOI:10.1021/ac00003a013

upstream raw materials:

octadecylamine hydrochloride

benzoyl chloride

1-aminooctadecane

benzoic acid

Downstream raw materials:

N-Octadecyl-benzimidic acid ethyl ester

Refernces

• 1、 Qian, Pu,Nanjo, Hiroshi,Yokoyama, Toshiro,Suzuki, Toshishige M.. "Characteristic molecular patterns formed by N-octadecylbenzamide and N-8-quinolyloctadecanamide self-assembled on a graphite surface". . p. 1229 - 1230. Retrieved 1999.
• 2、 Ding, Jiaoyang,Cao, Liping,Wang, Jungang,Xue, Weijian,Zhu, Yanping,Wu, Anxin. "The conversion of aryl and heteroaryl methylketones to the corresponding secondary or tertiary amides". experimental part. p. 298 - 301. Retrieved 2011/10/02.