3,5-Difluoro-2,4-dimethoxyaniline

Base Information

Chemical Name:3,5-Difluoro-2,4-dimethoxyaniline
CAS No.:195136-67-5
Molecular Formula:C8H9F2NO2
Molecular Weight:189.162
Hs Code.:
DSSTox Substance ID:DTXSID301287127
Mol file:195136-67-5.mol

Synonyms:3,5-Difluoro-2,4-dimethoxyaniline;195136-67-5;2,4-Dimethoxy-3,5-difluorobenzenamine;1-amino-3,5-difluoro-2,4-dimethoxybenzene;SCHEMBL6371958;IWVNUSZUKBDACW-UHFFFAOYSA-N;DTXSID301287127;MFCD12547867;AKOS006346336;3,5-Difluoro-2,4-dimethoxybenzenamine;CS-0242104;EN300-244810;F81951;Z1201626608

Suppliers and Price of 3,5-Difluoro-2,4-dimethoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,4-Dimethoxy-3,5-difluorobenzenamine
250mg
$ 165.00

Crysdot
3,5-Difluoro-2,4-dimethoxyaniline 95+%
5g
$ 1363.00

AK Scientific
3,5-Difluoro-2,4-dimethoxyaniline
2.5g
$ 1535.00

AK Scientific
3,5-Difluoro-2,4-dimethoxyaniline
1g
$ 831.00

AK Scientific
3,5-Difluoro-2,4-dimethoxyaniline
100mg
$ 310.00

Total 3 raw suppliers

Chemical Property of 3,5-Difluoro-2,4-dimethoxyaniline

Chemical Property:

PSA：44.48000
LogP:2.14540
XLogP3:1.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:2
Exact Mass:189.06013485
Heavy Atom Count:13
Complexity:170

Purity/Quality:

99%+ ^*data from raw suppliers

2,4-Dimethoxy-3,5-difluorobenzenamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1N)F)OC)F
Uses 2,4-DiMethoxy-3,5-difluorobenzenaMine is a reagent used in the preparation of highly potent acyl protein thioesterase inhibitors with potential application to Huntington’s disease treatment. 1,3-Dimethoxy-2,4-difluorobenzene is a reagent used in the preparation of highly potent acyl protein thioesterase inhibitors with potential application to Huntington’s disease treatment.

Technology Process of 3,5-Difluoro-2,4-dimethoxyaniline

There total 4 articles about 3,5-Difluoro-2,4-dimethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 195136-63-1
1,3-difluoro-2,4-dimethoxy-5-nitrobenzene

: 195136-67-5
1-amino-3,5-difluoro-2,4-dimethoxybenzene

Guidance literature:: With hydrogen; 10% palladium on activated carbon; In ethanol; ethyl acetate; for 2h; under 2068.65 Torr;

Reference yield: 98.0%

: 67-56-1
methanol

: 195136-63-1
1,3-difluoro-2,4-dimethoxy-5-nitrobenzene

: 195136-67-5
1-amino-3,5-difluoro-2,4-dimethoxybenzene

Guidance literature:: With palladium 10% on activated carbon; ammonium formate; In methanol; at 20 ℃; for 4h;
DOI:10.3998/ark.5550190.p009.011

Reference yield:

: 5580-79-0
2,3,4,5-tetrafluoro-1-nitrobenzene

: 195136-67-5
1-amino-3,5-difluoro-2,4-dimethoxybenzene

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / methanol / Ambient temperature

2: 99.8 percent / H₂ / Pd/C / ethanol; ethyl acetate / 2068.6 Torr

With hydrogen; palladium on activated charcoal; In methanol; ethanol; ethyl acetate;
DOI:10.1021/jo9706178