Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Base Information

Chemical Name:Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
CAS No.:198826-86-7
Molecular Formula:C11H18N2O3
Molecular Weight:226.276
Hs Code.:2933599090
DSSTox Substance ID:DTXSID60394755
Nikkaji Number:J885.748B
ChEMBL ID:CHEMBL414866
Mol file:198826-86-7.mol

Synonyms:198826-86-7;ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate;Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate;ethyl 6-methyl-2-oxo-4-propan-2-yl-3,4-dihydro-1H-pyrimidine-5-carboxylate;UPCMLD00WJAB97;Oprea1_203820;MLS000563004;CHEMBL414866;UPCMLD00WJAB97:002;DTXSID60394755;HMS2219O03;HMS3347C12;CMLD4_000054;MFCD00486526;AKOS005071937;BD-0109;SB57905;SDCCGMLS-0091588.P001;SMR000389025;EU-0084440;SR-01000513036;J-521035;SR-01000513036-1;Ethyl4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate;1,2,3,4-Tetrahydro-2-oxo-4-isopropyl-6-methylpyrimidine-5-carboxylic acid ethyl ester;ethyl 6-methyl-2-oxo-4-(propan-2-yl)-1,2,3,4-tetrahydropyrimidine-5-carboxylate

Suppliers and Price of Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Ethyl4-Isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
100mg
$ 60.00

Matrix Scientific
Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95%
1g
$ 151.00

Matrix Scientific
Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95%
500mg
$ 118.00

Matrix Scientific
Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate >95%
5g
$ 346.00

Crysdot
Ethyl4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxylate 95+%
10g
$ 357.00

AK Scientific
Ethyl4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
5g
$ 517.00

AK Scientific
Ethyl4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
1g
$ 253.00

AK Scientific
Ethyl4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate
500mg
$ 209.00

Total 5 raw suppliers

Chemical Property of Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

Chemical Property:

Melting Point:198-200°
PSA：70.92000
LogP:1.12970
XLogP3:1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:226.13174244
Heavy Atom Count:16
Complexity:334

Purity/Quality:

98%Min ^*data from raw suppliers

Ethyl4-Isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=C(NC(=O)NC1C(C)C)C

Technology Process of Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate

There total 5 articles about Ethyl 4-isopropyl-6-methyl-2-oxo-1,2,3,4-tetrahydro-5-pyrimidinecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 141-97-9
ethyl acetoacetate

: 78-84-2
isobutyraldehyde

: 57-13-6
urea

: 198826-86-7
5-(ethoxycarbonyl)-4-isopropyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: With silica-supported fluoroboric acid; In ethanol; at 20 ℃; for 2h;
DOI:10.1002/cjoc.201090084

Reference yield: 70.0%

: 198826-90-3
ethyl 2-methoxy-6-methyl-4-(1-methylethyl)-1,4-dihydropyrimidine-5-carboxylate

: 198826-86-7
5-(ethoxycarbonyl)-4-isopropyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; methanol; for 6h; Heating;
DOI:10.3987/com-97-7931

Reference yield: 60.0%

: 141-97-9
ethyl acetoacetate

: 57-13-6
urea

: 122-03-2
(4-isopropylbenzaldehyde)

: 198826-86-7
5-(ethoxycarbonyl)-4-isopropyl-6-methyl-3,4-dihydropyrimidin-2(1H)-one

Guidance literature:: With N,N'-ethylenebis(salicylideneiminato)iron(II); In glycerol; for 0.116667h; Microwave irradiation;
DOI:10.1007/s11243-012-9665-5