Quinoline, 5,7-dimethyl-

Base Information

• Chemical Name: Quinoline, 5,7-dimethyl-
• CAS No.: 20150-89-4
• Molecular Formula: C11H11N
• Molecular Weight: 157.21200
• DSSTox Substance ID: DTXSID00455314
• Nikkaji Number: J1.233.699C
• Wikidata: Q82277265
• Mol file: 20150-89-4.mol

Synonyms:5,7-dimethylquinoline;Quinoline, 5,7-dimethyl-;20150-89-4;SCHEMBL3969039;DTXSID00455314;AKOS006373889;EN300-128698

Chemical Property of Quinoline, 5,7-dimethyl-

Chemical Property:

• Vapor Pressure: 0.009mmHg at 25°C
• Melting Point: 22 °C
• Boiling Point: 273.818oC at 760 mmHg
• PKA: 5.72±0.26(Predicted)
• Flash Point: 113.494oC
• PSA: 12.89000
• Density: 1.053g/cm3
• LogP: 2.85160
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 0
• Exact Mass: 157.089149355
• Heavy Atom Count: 12
• Complexity: 155

Purity/Quality:

5,7-dimethyl-Quinoline 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C2C=CC=NC2=C1)C

Technology Process of Quinoline, 5,7-dimethyl-

There total 10 articles about Quinoline, 5,7-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tripropanolamine (14002-34-7) + 5-nitro-m-xylene (99-12-7) → 5,7-dimethylquinoline (20150-89-4)

Guidance literature:

With triphenylphosphine; isopropyl alcohol; tin(ll) chloride; ruthenium trichloride; In 1,4-dioxane; water; at 180 ℃; for 20h;

DOI:10.1002/jhet.5570400530

Reference yield: 70.0%

3,5-dimethylaminoaniline (108-69-0) + allyl alcohol (107-18-6) → 5,7-dimethylquinoline (20150-89-4)

Guidance literature:

With dipotassium peroxodisulfate; oxygen; silver carbonate; potassium iodide; at 120 ℃; for 12h; under 760.051 Torr; Schlenk technique;

DOI:10.1002/chem.201703218

Reference yield: 66.0%

1,2-bis(3,5-dimethylphenyl)diazene (77611-71-3) + allyl bromide (106-95-6) → 5,7-dimethylquinoline (20150-89-4)

Guidance literature:

With copper(l) iodide; In 1,2-dichloro-ethane; at 120 ℃; for 12h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.5b03009

upstream raw materials:

3,5-dimethylaminoaniline

glycerol

propan-1-ol-3-amine

3-Dimethylamino-1-propanol

Downstream raw materials:

5,7-dimethyl-1,2,3,4-tetrahydroquinoline