Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]-

Base Information

• Chemical Name: Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]-
• CAS No.: 20152-34-5
• Molecular Formula: C13H26OSi
• Molecular Weight: 226.434
• DSSTox Substance ID: DTXSID20447716
• Nikkaji Number: J513.822A
• Mol file: 20152-34-5.mol

Synonyms:Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]-;20152-34-5;DTXSID20447716;2-(tert-Butyldimethylsiloxy)-3-methylcyclohexene

Chemical Property of Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]-

Chemical Property:

• Boiling Point: 223.1±8.0 °C(Predicted)
• PSA: 9.23000
• Density: 0.86±0.1 g/cm3(Predicted)
• LogP: 4.71210
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 226.175291983
• Heavy Atom Count: 15
• Complexity: 248

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CCCC=C1O[Si](C)(C)C(C)(C)C

Technology Process of Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]-

There total 7 articles about Silane, (1,1-dimethylethyl)dimethyl[(6-methyl-1-cyclohexen-1-yl)oxy]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

tert-butyldimethylsilyl chloride (18162-48-6) + 2-Methylcyclohexanone (583-60-8) → 1-tert-butyldimethylsilyloxy-6-methyl-1-cyclohexene (20152-34-5) + 1-tert-butyldimethylsilyloxy-2-methyl-1-cyclohexene (20152-33-4)

Guidance literature:

With N,N,N,N,N,N-hexamethylphosphoric triamide; potassium hydride; In tetrahydrofuran; at -78 - 25 ℃; for 3h;

DOI:10.1016/S0040-4039(01)91129-3

Reference yield: 73.0%

t-butyldimethylsiyl triflate (69739-34-0) + 2-Methylcyclohexanone (583-60-8) → 1-tert-butyldimethylsilyloxy-6-methyl-1-cyclohexene (20152-34-5)

Guidance literature:

2-Methylcyclohexanone; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -78 ℃; for 0.833333h; Inert atmosphere;

t-butyldimethylsiyl triflate; In tetrahydrofuran; hexane; at -78 - 20 ℃; for 1.5h; Inert atmosphere;

DOI:10.3762/bjoc.8.73

Reference yield:

t-butyldimethylsiyl triflate (69739-34-0) + 2-Methylcyclohexanone (583-60-8) → 1-tert-butyldimethylsilyloxy-6-methyl-1-cyclohexene (20152-34-5) + 1-tert-butyldimethylsilyloxy-2-methyl-1-cyclohexene (20152-33-4)

Guidance literature:

With triethylamine; In dichloromethane; for 0.0833333h; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(01)81731-7

upstream raw materials:

tert-butyldimethylsilyl chloride

2-Methylcyclohexanone

t-butyldimethylsiyl triflate

N,O-bis(tertbutyldimethylsilyl)acetamide

Downstream raw materials:

1-(tert-Butyl-dimethyl-silanyloxy)-2-methyl-cyclohexyl-hydroperoxide

1-tert-butyldimethylsilyloxy-2-methyl-1-cyclohexene

2-Methylcyclohexanone

diethyl 6-methylcyclohex-1-enyl phosphate