Cyclohexane, 1-chloro-2-fluoro-, trans-

Base Information

• Chemical Name: Cyclohexane, 1-chloro-2-fluoro-, trans-
• CAS No.: 20421-40-3
• Molecular Formula: C6H10ClF
• Molecular Weight: 136.597
• Mol file: 20421-40-3.mol

Synonyms:

Chemical Property of Cyclohexane, 1-chloro-2-fluoro-, trans-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Cyclohexane, 1-chloro-2-fluoro-, trans-

There total 14 articles about Cyclohexane, 1-chloro-2-fluoro-, trans- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

cyclohexene (110-83-8) → trans-2-chlorocyclohexanol (6628-80-4) + trans-2-chlorocyclohexyl acetate (33815-66-6,35998-47-1,36375-66-3) + trans-1-chloro-2-fluorocyclohexane (20421-40-3)

Guidance literature:

With lead(IV) acetate; hydrogen fluoride; sodium chloride; copper dichloride; Yield given;

Reference yield: 70.0%

acetic acid (64-19-7,77671-22-8) + cyclohexene (110-83-8) → trans-2-chlorocyclohexyl acetate (33815-66-6,35998-47-1,36375-66-3) + trans-1-chloro-2-fluorocyclohexane (20421-40-3)

Guidance literature:

With lead(II,IV) oxide; hydrogen fluoride; copper dichloride; In 1,1,2-Trichloro-1,2,2-trifluoroethane; for 1.5h;

Reference yield: 60.0%

cyclohexene (110-83-8) → (+/-)-(trans-2-chloro-cyclohexyl)-methyl-amine + trans-1-chloro-2-fluorocyclohexane (20421-40-3)

Guidance literature:

With boron trifluoride diethyl etherate; In dichloromethane; Ambient temperature; further clorinating agents (for example: N-chlorosuccinimide );

DOI:10.1016/S0040-4039(00)94744-0

upstream raw materials:

fluorocyclohexane

N-chloro-succinimide

cyclohexene

acetic acid

Downstream raw materials:

1-fluorocyclohexene