3''-CHLOROCHALCONE

Base Information

• Chemical Name: 3''-CHLOROCHALCONE
• CAS No.: 20426-48-6
• Molecular Formula: C15H11ClO
• Molecular Weight: 242.705
• Hs Code.: 2914700090
• Mol file: 20426-48-6.mol

Synonyms:2-Propen-1-one, 1-(3-chlorophenyl)-3-phenyl-;3'-Chlor-chalcon;6-chloro-2-phenyl-4H-chromen-4-one;3'-CHLOROCHALCONE;

Chemical Property of 3''-CHLOROCHALCONE

Chemical Property:

• Melting Point: 93 °C
• Boiling Point: 388.2±42.0 °C(Predicted)
• PSA: 17.07000
• Density: 1.202±0.06 g/cm3(Predicted)
• LogP: 4.23610

Purity/Quality:

99% ^*data from raw suppliers

3'-CHLOROCHALCONE Aldrich ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3''-CHLOROCHALCONE

There total 7 articles about 3''-CHLOROCHALCONE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzaldehyde (100-52-7) + 3'-Chloroacetophenone (99-02-5) → (E)-1-(3-chlorophenyl)-3-phenylprop-2-en-1-one (20426-48-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; for 4h; Cooling with ice;

DOI:10.1002/bkcs.11749

Reference yield: 94.8%

benzaldehyde (100-52-7) + 3'-Chloroacetophenone (99-02-5) → 6-chloro-2-phenyl-4H-chromen-4-one (20426-48-6)

Guidance literature:

With potassium hydroxide; In ethanol; water; at 25 ℃;

DOI:10.1002/bkcs.11813

Reference yield: 86.0%

m-chlorophenylacetylene (766-83-6) + benzaldehyde (100-52-7) → 6-chloro-2-phenyl-4H-chromen-4-one (20426-48-6)

Guidance literature:

With Hβ zeolite; In water; at 100 ℃; for 20h; Sealed tube;

DOI:10.1039/c6ra11593d

upstream raw materials:

benzaldehyde

3'-Chloroacetophenone

m-chlorophenylacetylene

m-Chlorobenzaldehyde

Downstream raw materials:

6-(3-Chloro-phenyl)-4-phenyl-3,4-dihydro-1H-pyrimidin-2-one

4-Chloro-3-phenyl-indan-1-on

6-chloro-3-phenyl-2,3-dihydro-1H-inden-1-one

(2R,3S)-2,3-epoxy-1-(3-chlorophenyl)-3-phenylpropan-1-one