BIS(4-METHOXYPHENYL)PHOSPHINIC ACID

Base Information

• Chemical Name: BIS(4-METHOXYPHENYL)PHOSPHINIC ACID
• CAS No.: 20434-05-3
• Molecular Formula: C14H15O4P
• Molecular Weight: 278.244
• Hs Code.: 2918990090
• Mol file: 20434-05-3.mol

Synonyms:di(p-methoxyphenyl)phosphinic acid;Bis-(4-methoxy-phenyl)-phosphinsaeure;bis-p-methoxyphenylphosphinic acid;di-p-anisylphosphinic acid;bis(p-methoxyphenyl)phosphonic acid;bis-(4-methoxy-phenyl)-phosphinic acid;

Chemical Property of BIS(4-METHOXYPHENYL)PHOSPHINIC ACID

Chemical Property:

• Vapor Pressure: 5.55E-11mmHg at 25°C
• Melting Point: 185-187oC(lit.)
• Boiling Point: 504.1oC at 760 mmHg
• Flash Point: 258.7oC
• PSA: 65.57000
• Density: 1.27g/cm3
• LogP: 1.92500
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Bis(4-methoxyphenyl)phosphinic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Uses: Bis(4-methoxyphenyl)phosphinic acid was used to treat the chemical surface of porphyrin-sensitised titania films after dye adsorption to enhance the efficiency of dye-sensitized solar cells (DSSC). Bis(4-methoxyphenyl)phosphinic Acid acts as a reagent in the synthesis of phosphonic acids, aromatic phosphonic acids and their derivatives.

Technology Process of BIS(4-METHOXYPHENYL)PHOSPHINIC ACID

There total 8 articles about BIS(4-METHOXYPHENYL)PHOSPHINIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

1-bromo-4-methoxy-benzene (104-92-7) → bis(4-methoxyphenyl)phosphinic acid (20434-05-3)

Guidance literature:

1-bromo-4-methoxy-benzene; With tris(dibenzylideneacetone)dipalladium⁽⁰⁾ chloroform complex; anilinium hypophosphite; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In tetrahydrofuran; at 120 ℃; Microwave irradiation; Inert atmosphere;

With sodium hydroxide; In diethyl ether; water;

With hydrogenchloride; In water;

DOI:10.1016/j.tet.2009.10.028

Reference yield: 83.0%

ethyl bis(4-methoxyphenyl)phosphinate (1454907-96-0) → bis(4-methoxyphenyl)phosphinic acid (20434-05-3)

Guidance literature:

With sodium hydroxide; In water; at 80 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.6b03283

Reference yield: 69.0%

bis(4-methoxyphenyl)phosphine oxide (15754-51-5) → bis(4-methoxyphenyl)phosphinic fluoride + bis(4-methoxyphenyl)phosphinic acid (20434-05-3)

Guidance literature:

With 4-(difluoroiodo)toluene; In chlorobenzene; at 60 ℃; for 0.166667h; Solvent; Temperature; Reagent/catalyst; Inert atmosphere;

DOI:10.1016/j.tetlet.2018.06.044

upstream raw materials:

bis(4-methoxyphenyl)phosphine oxide

N,N-diethylphosphoramidous dichloride

4-methoxyphenyl magnesium bromide

1-bromo-4-methoxy-benzene

Downstream raw materials:

methyl bis(4-methoxyphenyl)phosphinate

1-(2-bromophenyl)ethenyl di(4-methoxyphenyl)phosphinate

O-(bis-p-methoxyphenylphosphinyl)hydroxylamine

O-(bis-p-methoxyphenylphosphinyl)acetone oxime