(R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine

Base Information

Chemical Name:(R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine
CAS No.:207923-14-6
Molecular Formula:C10H18N2O2
Molecular Weight:198.265
Hs Code.:
DSSTox Substance ID:DTXSID90467229
Nikkaji Number:J1.175.783I
Mol file:207923-14-6.mol

Synonyms:207923-14-6;(R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine;(2r)-2-isopropyl-3,6-dimethoxy-5-methyl-2,5-dihydropyrazine;(5R)-3,6-dimethoxy-2-methyl-5-propan-2-yl-2,5-dihydropyrazine;(2r,5Sr)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine;SCHEMBL1835656;DTXSID90467229;AGSVBAIKOLJRNR-BRFYHDHCSA-N;AT33020;(5R)-3, 6-dimethoxy-2-methyl-5-propan-2-yl-2, 5-dihydropyrazine

Suppliers and Price of (R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(2R,5SR)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYL-5- METHYLPYRAZINE 95.00%
5MG
$ 499.46

Total 4 raw suppliers

Chemical Property of (R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine

Chemical Property:

Boiling Point:256.5±33.0 °C(Predicted)
PKA:3.85±0.70(Predicted)
PSA：43.18000
Density:1.08±0.1 g/cm3(Predicted)
LogP:0.37410
XLogP3:1.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:198.136827821
Heavy Atom Count:14
Complexity:259

Purity/Quality:

98%Min ^*data from raw suppliers

(2R,5SR)-(-)-2,5-DIHYDRO-3,6-DIMETHOXY-2-ISOPROPYL-5- METHYLPYRAZINE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1C(=NC(C(=N1)OC)C(C)C)OC
Isomeric SMILES:CC1C(=N[C@@H](C(=N1)OC)C(C)C)OC

Technology Process of (R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine

There total 1 articles about (R)-(-)-2,5-dihydro-3,6-dimethoxy-2-isopropyl-5-methylpyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.5%

: 109838-85-9
(2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine

: 74-88-4
methyl iodide

: 207923-14-6
(6R)-6-isopropyl-5-methoxy-3-methyl-3,6-dihydro-2-pyrazinyl methyl ether

Guidance literature:: (2R)-2,5-dihydro-2-isopropyl-3,6-dimethoxypyrazine; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -78 ℃; for 2.5h;

Reference yield: 90.0%

: 207923-14-6
(6R)-6-isopropyl-5-methoxy-3-methyl-3,6-dihydro-2-pyrazinyl methyl ether

: 3-(3',3'-Dimethyltriazeno)benzyl bromide

: C₁₉H₂₉N₅O₂

Guidance literature:: (6R)-6-isopropyl-5-methoxy-3-methyl-3,6-dihydro-2-pyrazinyl methyl ether; With 1,3-dimethyl-2-imidazolidinone; n-butyllithium;

3-(3',3'-Dimethyltriazeno)benzyl bromide;
DOI:10.1016/S0022-1139(00)00377-8

Reference yield: 83.0%

: 100-39-0
benzyl bromide

: 207923-14-6
(6R)-6-isopropyl-5-methoxy-3-methyl-3,6-dihydro-2-pyrazinyl methyl ether

: (2S,5R)-2-Benzyl-5-isopropyl-3,6-dimethoxy-2-methyl-2,5-dihydro-pyrazine

Guidance literature:: (6R)-6-isopropyl-5-methoxy-3-methyl-3,6-dihydro-2-pyrazinyl methyl ether; With tert.-butyl lithium; In tetrahydrofuran; at -78 ℃;

benzyl bromide; In tetrahydrofuran; at -78 - 0 ℃;
DOI:10.1055/s-2003-42103