(1-ethyl-1H-benzimidazol-2-yl)methanol

Base Information

Chemical Name:(1-ethyl-1H-benzimidazol-2-yl)methanol
CAS No.:21269-78-3
Molecular Formula:C10H12N2O
Molecular Weight:176.21500
Hs Code.:2933990090
European Community (EC) Number:696-395-8
DSSTox Substance ID:DTXSID60355407
Wikidata:Q82134292
Mol file:21269-78-3.mol

Synonyms:(1-ethyl-1H-benzimidazol-2-yl)methanol;21269-78-3;(1-ethylbenzimidazol-2-yl)methanol;(1-Ethyl-1H-benzoimidazol-2-yl)-methanol;(1-ETHYL-1H-BENZO[D]IMIDAZOL-2-YL)METHANOL;(1-ethyl-1H-1,3-benzodiazol-2-yl)methanol;1-ethyl-2-hydroxymethylbenzimidazole;(1-ethyl-1h-benzoimidazol-2-yl)methanol;1h-benzimidazole-2-methanol, 1-ethyl-;F0414-0076;SCHEMBL2017366;DTXSID60355407;YPMCFIDLEKUBHI-UHFFFAOYSA-N;MFCD00964668;STK214105;AKOS000272102;1-ethyl-2-(hydroxymethyl)benzimidazole;LS-01319;BB 0219482;CS-0073225;FT-0768768;EN300-36566;D96812;AB00667760-01;AE-907/30533056;Z57299967

Suppliers and Price of (1-ethyl-1H-benzimidazol-2-yl)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1-Ethyl-2-hydroxymethylbenzimidazole
5g
$ 1405.00

Matrix Scientific
(1-Ethyl-1H-benzimidazol-2-yl)methanol
1g
$ 308.00

Matrix Scientific
(1-Ethyl-1H-benzimidazol-2-yl)methanol
500mg
$ 200.00

Crysdot
(1-Ethyl-1H-benzo[d]imidazol-2-yl)methanol 95+%
1g
$ 225.00

Chemenu
(1-ethyl-1H-benzimidazol-2-yl)methanol 95%
1g
$ 274.00

ChemBridge Corporation
(1-ethyl-1H-benzimidazol-2-yl)methanol 95%
1 g
$ 70.00

American Custom Chemicals Corporation
(1-ETHYL-1H-BENZIMIDAZOL-2-YL)METHANOL 95.00%
5G
$ 1168.42

American Custom Chemicals Corporation
(1-ETHYL-1H-BENZIMIDAZOL-2-YL)METHANOL 95.00%
2.5G
$ 983.88

American Custom Chemicals Corporation
(1-ETHYL-1H-BENZIMIDAZOL-2-YL)METHANOL 95.00%
1G
$ 721.57

Alichem
(1-Ethyl-1H-benzo[d]imidazol-2-yl)methanol
1g
$ 220.50

Total 12 raw suppliers

Chemical Property of (1-ethyl-1H-benzimidazol-2-yl)methanol

Chemical Property:

Vapor Pressure:9.9E-06mmHg at 25°C
Melting Point:143 °C
Boiling Point:357.5oC at 760 mmHg
PKA:13.81±0.10(Predicted)
Flash Point:170oC
PSA：38.05000
Density:1.18g/cm3
LogP:1.54850
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:176.094963011
Heavy Atom Count:13
Complexity:174

Purity/Quality:

99%, ^*data from raw suppliers

1-Ethyl-2-hydroxymethylbenzimidazole ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCN1C2=CC=CC=C2N=C1CO
Uses 1-Ethyl-2-hydroxymethylbenzimidazole is an intermediate used in the synthesis of N-pyrimidinyl-4-aminobenzenesulfonamides useful for treatment or prevention of disease mediated by α2B-adrenoceptor. It is also used to prepare benzimidazole derivatives as ENaC blockers.

Technology Process of (1-ethyl-1H-benzimidazol-2-yl)methanol

There total 6 articles about (1-ethyl-1H-benzimidazol-2-yl)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 4856-97-7
2-(Hydroxymethyl)benzimidazole

: 75-03-6
ethyl iodide

: 21269-78-3
(1-ethyl-1H-benzo[d]imidazol-2-yl)methanol

Guidance literature:: 2-(Hydroxymethyl)benzimidazole; With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 0.333333h;

ethyl iodide; In N,N-dimethyl-formamide; at 60 ℃; for 10h;

Reference yield: 68.0%

: 4856-97-7
2-(Hydroxymethyl)benzimidazole

: 21269-78-3
(1-ethyl-1H-benzo[d]imidazol-2-yl)methanol

Guidance literature:: 2-(Hydroxymethyl)benzimidazole; With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 0.333333h;

ethyl halide; In N,N-dimethyl-formamide; at 60 ℃;
DOI:10.1016/j.bmc.2021.116352