5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine

Base Information

Chemical Name:5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine
CAS No.:21822-27-5
Molecular Formula:C15H20N4O3
Molecular Weight:304.349
Hs Code.:
DSSTox Substance ID:DTXSID201169500
Nikkaji Number:J796.927I
ChEMBL ID:CHEMBL325533
Mol file:21822-27-5.mol

Synonyms:CHEMBL325533;DTXSID201169500;BDBM50138701;5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine;6-Methyl-5-(3,4,5-trimethoxy-benzyl)-pyrimidine-2,4-diamine;6-methyl-5-(3,4,5-trimethoxybenzyl)pyrimidine-2,4-diamine;6-Methyl-5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine;21822-27-5

Suppliers and Price of 5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:5
Exact Mass:304.15354051
Heavy Atom Count:22
Complexity:333

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C(=NC(=N1)N)N)CC2=CC(=C(C(=C2)OC)OC)OC

Technology Process of 5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine

There total 5 articles about 5-(3,4,5-Trimethoxybenzyl)-6-methylpyrimidine-2,4-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.0%

: 4-(2,4-Diamino-6-methyl-pyrimidin-5-ylmethyl)-2,6-dimethoxy-phenol

: 74-88-4
methyl iodide

: 21822-27-5
2,4-diamino-6-methyl-5-(3',4',5'-trimethoxybenzyl)pyrimidine

Guidance literature:: With sodium methylate; In dimethyl sulfoxide; for 4h; Ambient temperature;
DOI:10.1021/jm00178a007

Reference yield:

: 410535-87-4
3-oxo-2-(3,4,5-trimethoxy-benzyl)-butyronitrile

: 21822-27-5
2,4-diamino-6-methyl-5-(3',4',5'-trimethoxybenzyl)pyrimidine

Guidance literature:: Multi-step reaction with 2 steps

1: dioxane

2: DMSO / ethanol

With dimethyl sulfoxide; In 1,4-dioxane; ethanol;
DOI:10.1021/ac070215s