1H-Indole, 1-benzoyl-5-methoxy-

Base Information

Chemical Name:1H-Indole, 1-benzoyl-5-methoxy-
CAS No.:21859-82-5
Molecular Formula:C16H13NO2
Molecular Weight:251.285
Hs Code.:
ChEMBL ID:CHEMBL189253
DSSTox Substance ID:DTXSID70473606
Nikkaji Number:J2.111.062K
Wikidata:Q82303112
Mol file:21859-82-5.mol

Synonyms:21859-82-5;1H-Indole, 1-benzoyl-5-methoxy-;(5-Methoxy-1H-indol-1-yl)(phenyl)methanone;(5-methoxyindol-1-yl)-phenylmethanone;1-Benzoyl-5-methoxy-1H-indole;CHEMBL189253;DTXSID70473606

Suppliers and Price of 1H-Indole, 1-benzoyl-5-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 1H-Indole, 1-benzoyl-5-methoxy-

Chemical Property:

PSA：31.23000
LogP:3.33840
XLogP3:3.5
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:251.094628657
Heavy Atom Count:19
Complexity:325

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)N(C=C2)C(=O)C3=CC=CC=C3

Technology Process of 1H-Indole, 1-benzoyl-5-methoxy-

There total 5 articles about 1H-Indole, 1-benzoyl-5-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 1006-94-6
5-methoxylindole

: 4231-62-3
1-benzoyl-1H-benzotriazole

: 21859-82-5
(5-methoxy-1H-indol-1-yl)(phenyl)methanone

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 25 ℃;
DOI:10.1055/s-2007-990889

Reference yield: 75.0%

: 1006-94-6
5-methoxylindole

: 98-88-4
benzoyl chloride

: 21859-82-5
(5-methoxy-1H-indol-1-yl)(phenyl)methanone

Guidance literature:: 5-methoxylindole; With sodium t-butanolate; In tetrahydrofuran; at 20 ℃;

benzoyl chloride; In tetrahydrofuran;
DOI:10.1021/jm049802l

Reference yield: 56.0%

: 1006-94-6
5-methoxylindole

: 100-52-7
benzaldehyde

: 21859-82-5
(5-methoxy-1H-indol-1-yl)(phenyl)methanone

Guidance literature:: With 2-mesityl-2,5,6,7-tetrahydropyrrolo[2,1-c][1,2,4]triazolium chloride; 3,5,3',5'-tetra-tert-butyl-4,4'-diphenoquinone; 1,8-diazabicyclo[5.4.0]undec-7-ene; In dichloromethane; at 20 ℃; for 24h; chemoselective reaction; Molecular sieve; Sealed tube;
DOI:10.1039/c7cc08672e