2-Chloroethyl methylcarbamate

Base Information

• Chemical Name: 2-Chloroethyl methylcarbamate
• CAS No.: 22074-92-6
• Molecular Formula: C4H8ClNO2
• Molecular Weight: 137.566
• Hs Code.: 2924199090
• European Community (EC) Number: 632-696-2
• Mol file: 22074-92-6.mol

Synonyms:2-Chloroethyl methylcarbamate;22074-92-6;SCHEMBL8282495;AKOS006278951

Chemical Property of 2-Chloroethyl methylcarbamate

Chemical Property:

• Melting Point: 19 °C
• Boiling Point: 110-112 °C(Press: 15 Torr)
• PSA: 38.33000
• Density: 1.163±0.06 g/cm3(Predicted)
• LogP: 0.97210
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 137.0243562
• Heavy Atom Count: 8
• Complexity: 76.4

Purity/Quality:

99% ^*data from raw suppliers

2-CHLOROETHYL METHYLCARBAMATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC(=O)OCCCl

Technology Process of 2-Chloroethyl methylcarbamate

There total 6 articles about 2-Chloroethyl methylcarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylamine hydrochloride (593-51-1) + 2-Chloroethyl chloroformate (627-11-2) → methyl-carbamic acid-(2-chloro-ethyl ester) (22074-92-6)

Guidance literature:

With sodium carbonate;

DOI:10.1021/ja01853a064

Reference yield:

methylcarbamic 2-hydroxyethylester (13296-57-6) → methyl-carbamic acid-(2-chloro-ethyl ester) (22074-92-6)

Guidance literature:

With thionyl chloride;

Reference yield:

N-methylimide carbonyldichloride (5652-90-4) + ethylene glycol (107-21-1) → methyl-carbamic acid-(2-chloro-ethyl ester) (22074-92-6)

Guidance literature:

With hydrogenchloride; In dichloromethane;

upstream raw materials:

methylcarbamic 2-hydroxyethylester

methylamine hydrochloride

2-Chloroethyl chloroformate

dimethyl amine

Downstream raw materials:

3-methyl-2-oxo-1,3-oxazolidine

(2-hydroxyethyl)(methyl)amine

methyl-nitroso-carbamic acid-(2-chloro-ethyl ester)

N-Methylcarbachol chloride