Carbonic acid methyl(4-methoxyphenyl) ester

Base Information

• Chemical Name: Carbonic acid methyl(4-methoxyphenyl) ester
• CAS No.: 22159-41-7
• Molecular Formula: C9H10O4
• Molecular Weight: 182.176
• Mol file: 22159-41-7.mol

Synonyms:p-methoxyphenyl anilinoformate;methyl p-methoxyphenyl carbonate;4-Methoxyphenyl-methylcarbonat;methyl 4-methoxyphenyl carbonate;4-(methoxycarbonyloxy)anisole;4-methoxyphenylmethylcarbonate;

Chemical Property of Carbonic acid methyl(4-methoxyphenyl) ester

Chemical Property:

• PSA: 44.76000
• LogP: 1.84040

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Carbonic acid methyl(4-methoxyphenyl) ester

There total 8 articles about Carbonic acid methyl(4-methoxyphenyl) ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.9%

4-methoxy-phenol (150-76-5) + methyl chloroformate (79-22-1) → methyl 4-methoxyphenyl carbonate (22159-41-7)

Guidance literature:

With pyridine; In tetrahydrofuran; at 0 ℃; for 1h;

Reference yield: 79.0%

methanol (67-56-1) + carbon dioxide (124-38-9,18923-20-1) + 4-methoxy-phenol (150-76-5) → methyl 4-methoxyphenyl carbonate (22159-41-7)

Guidance literature:

With N,N,N',N'-tetramethylguanidine; In dimethyl sulfoxide; at 20 ℃; under 760.051 Torr; Irradiation; Sealed tube;

DOI:10.1039/d1cc05833a

Reference yield:

4-methoxy-phenol (150-76-5) + carbonic acid dimethyl ester (616-38-6) → methyl 4-methoxyphenyl carbonate (22159-41-7) + 1,4-dimethoxybezene (150-78-7)

Guidance literature:

With potassium carbonate; at 90 ℃; for 53h;

DOI:10.1021/jo048532b

upstream raw materials:

4-methoxy-phenol

methyl chloroformate

methanol

4-methoxyphenylchloroformate

Downstream raw materials:

2-[1-(5-Benzyloxy-2-methoxy-phenyl)-meth-(E)-ylidene]-3-oxo-butyric acid ethyl ester

ethyl 2-(2-methoxy-5-benzyloxyphenyl)-3-butanoate

2,4-diamino-5-methyl-6-(2'-methoxy-5'-hydroxybenzyl)pyrido[2,3-d]pyrimidine

2,4-diamino-5-methyl-6-(2'-methoxy-5'-benzyloxy)benzyl-7-chloropyrido[2,3-d]pyrimidine

Refernces

• 1、 -. "CYCLIC AMINES AS BROMODOMAIN INHIBITORS". Paragraph 0590; 0593. . Retrieved 2014/05/25.
• 2、 Neverov, Alexei A.,Chen, Leanne D.,George, Sean,Simon, David,Maxwell, Christopher I.,Brown, R. Stan. "A mechanistic study of the [La2(OCH3) 2]4+-and [(1,5,9-triazacyclodo-decane):Zn:(OCH 3)]+-catalyzed methanolysis of carbonates: Possible application for the recycling of bisphenol A polycar". . p. 1139 - 1146. Retrieved 2013/11/06.