N-Methoxy-6,N-dimethyl-nicotinamide

Base Information

Chemical Name:N-Methoxy-6,N-dimethyl-nicotinamide
CAS No.:221615-71-0
Molecular Formula:C9H12N2O2
Molecular Weight:180.206
Hs Code.:2933399990
DSSTox Substance ID:DTXSID10463667
Nikkaji Number:J1.644.861C
Wikidata:Q82288655
Mol file:221615-71-0.mol

Synonyms:221615-71-0;N-Methoxy-N,6-dimethylnicotinamide;N-METHOXY-6,N-DIMETHYL-NICOTINAMIDE;N-methoxy-N,6-dimethylpyridine-3-carboxamide;6-methylnicotinic acid N,O-dimethylhydroxylamide;SCHEMBL1436840;DTXSID10463667;FCAXSTPYTWGTPQ-UHFFFAOYSA-N;N-Methoxy-6,N-dimethyinicotinamide;N-Methoxy-6,N-dimethylnicotinamide;WIA61571;N-methoxy-N, 6-dimethylnicotinamide;MFCD09907654;N-methoxy-6, N-dimethyl-nicotinamide;AKOS009129793;N-methoxy-N-methyl-6-methylnicotinamide;AS-61873;N-methoxy-N-methyl-6-methyl-nicotinamide;CS-0131516;N-methoxy-N, 6-dimethylpyridine-3-carboxamide;A878677;N-methoxy-N-methyl-6-methylpyridine-3-carboxamide;F1903-0187;Z253322746

Suppliers and Price of N-Methoxy-6,N-dimethyl-nicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-Methoxy-N,6-dimethylnicotinamide 95+%
5g
$ 489.00

Chemenu
N-Methoxy-N,6-dimethylnicotinamide 95%
5g
$ 462.00

Apolloscientific
N-Methoxy-6,n-dimethyl-nicotinamide 95%
1g
$ 160.00

Apolloscientific
N-Methoxy-6,n-dimethyl-nicotinamide 95%
5g
$ 640.00

American Custom Chemicals Corporation
N-METHOXY-6-N-DIMETHYL-NICOTINAMIDE 95.00%
5MG
$ 497.70

Alichem
N-Methoxy-N,6-dimethylnicotinamide
5g
$ 543.40

Total 11 raw suppliers

Chemical Property of N-Methoxy-6,N-dimethyl-nicotinamide

Chemical Property:

PSA：42.43000
LogP:1.02340
XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:180.089877630
Heavy Atom Count:13
Complexity:185

Purity/Quality:

97% ^*data from raw suppliers

N-Methoxy-N,6-dimethylnicotinamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=C(C=C1)C(=O)N(C)OC

Technology Process of N-Methoxy-6,N-dimethyl-nicotinamide

There total 6 articles about N-Methoxy-6,N-dimethyl-nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 3222-47-7
6-methylnicotinic acid

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 221615-71-0
N-methoxy-N-methyl-6-methylnicotinamide

Guidance literature:: 6-methylnicotinic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 1h;

N,O-dimethylhydroxylamine*hydrochloride; With pyridine; In dichloromethane; at 0 - 20 ℃; for 18h;
DOI:10.1016/j.bmc.2019.02.025

Reference yield: 94.3%

: 5470-70-2
Methyl 6-methylnicotinate

: 1117-97-1
N,0-dimethylhydroxylamine

: 221615-71-0
N-methoxy-N-methyl-6-methylnicotinamide

Guidance literature:: With isopropylmagnesium chloride; In tetrahydrofuran; at -10 - 5 ℃; for 2.5h;

Reference yield: 62.0%

: 5470-70-2
Methyl 6-methylnicotinate

: 6638-79-5
N,O-dimethylhydroxylamine*hydrochloride

: 221615-71-0
N-methoxy-N-methyl-6-methylnicotinamide

Guidance literature:: N,O-dimethylhydroxylamine*hydrochloride; With dimethylaluminum chloride; In hexane; dichloromethane; at 0 ℃; for 1h; Inert atmosphere;

Methyl 6-methylnicotinate; In hexane; dichloromethane; at 20 ℃;