4-Methoxy-1,2-dihydrobenzocyclobutene-1-one

Base Information

Chemical Name:4-Methoxy-1,2-dihydrobenzocyclobutene-1-one
CAS No.:22246-27-1
Molecular Formula:C9H8O2
Molecular Weight:148.161
Hs Code.:
DSSTox Substance ID:DTXSID001250812
Nikkaji Number:J1.463.324C
Mol file:22246-27-1.mol

Synonyms:22246-27-1;4-Methoxy-1,2-dihydrobenzocyclobutene-1-one;Bicyclo[4.2.0]octa-1,3,5-trien-7-one, 3-methoxy-;3-methoxybicyclo[4.2.0]octa-1(6),2,4-trien-7-one;DTXSID001250812;AKOS004907574;3-METHOXYBICYCLO[4.2.0]OCTA-1,3,5-TRIEN-7-ONE

Suppliers and Price of 4-Methoxy-1,2-dihydrobenzocyclobutene-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-Methoxy-1,2-dihydrobenzocyclobutene-1-one

Chemical Property:

XLogP3:0.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:148.052429494
Heavy Atom Count:11
Complexity:176

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=CC2=C(C=C1)C(=O)C2

Technology Process of 4-Methoxy-1,2-dihydrobenzocyclobutene-1-one

There total 2 articles about 4-Methoxy-1,2-dihydrobenzocyclobutene-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 108-31-6
maleic anhydride

: 91416-36-3
(4-Methoxy-6-methylene-cyclohexa-2,4-dienylidene)-methanone

: 22246-27-1
4-methoxybenzocyclobutenone

: 35598-05-1
methyl 4-methoxy-2-methylbenzoate

: 7-Methoxy-9,9a-dihydro-3aH-naphtho[2,3-c]furan-1,3,4-trione

Guidance literature:: In diethyl ether; at 23 ℃; Title compound not separated from byproducts; Irradiation;
DOI:10.1016/S0040-4039(01)80210-0

Reference yield:

: 67-56-1
methanol

: 91416-36-3
(4-Methoxy-6-methylene-cyclohexa-2,4-dienylidene)-methanone

: 22246-27-1
4-methoxybenzocyclobutenone

: 35598-05-1
methyl 4-methoxy-2-methylbenzoate

: 7-Methoxy-9,9a-dihydro-3aH-naphtho[2,3-c]furan-1,3,4-trione

Guidance literature:: In diethyl ether; at 23 ℃; Title compound not separated from byproducts; Irradiation;
DOI:10.1016/S0040-4039(01)80210-0

Reference yield: 83.0%

: 22246-27-1
4-methoxybenzocyclobutenone

: 24395-14-0
N-(p-tolylsulfonyl)-2-phenylaziridine

: C₂₄H₂₃NO₄S

Guidance literature:: With bis(tri-t-butylphosphine)palladium⁽⁰⁾; bis(2,6-di-tert-butyl-4-methylphenoxide)methylaluminum; 2-[4,5-dihydro-1,3-oxazol-2-yl]pyridine; In acetonitrile; at 60 ℃; for 12h;
DOI:10.1038/s41557-021-00746-7