Bromo-chloro-acetic acid ethyl ester

Base Information

• Chemical Name: Bromo-chloro-acetic acid ethyl ester
• CAS No.: 22524-32-9
• Molecular Formula: C4H6BrClO2
• Molecular Weight: 201.447
• DSSTox Substance ID: DTXSID00519804
• Nikkaji Number: J3.407.741J
• Mol file: 22524-32-9.mol

Synonyms:22524-32-9;bromo-chloro-acetic acid ethyl ester;ETHYL 2-BROMO-2-CHLOROACETATE;Ethyl bromo(chloro)acetate;DTXSID00519804

Chemical Property of Bromo-chloro-acetic acid ethyl ester

Chemical Property:

• Refractive Index: 1.4639 (estimate)
• PSA: 26.30000
• Density: 1.5890
• LogP: 1.50930
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 199.92397
• Heavy Atom Count: 8
• Complexity: 86.1

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC(=O)C(Cl)Br

Technology Process of Bromo-chloro-acetic acid ethyl ester

There total 2 articles about Bromo-chloro-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-ethoxy-2-bromo-1,2-dichloro-ethene + acetic acid (64-19-7,77671-22-8) → ethyl 2-bromo-2-chloroacetate (22524-32-9) + acetyl chloride (75-36-5)

Guidance literature:

Reference yield:

1-ethoxy-2-bromo-1,2-dichloro-ethene + benzoic acid (65-85-0,8013-63-6) → ethyl 2-bromo-2-chloroacetate (22524-32-9) + benzoyl chloride (98-88-4)

Guidance literature:

Reference yield:

ethyl 2-bromo-2-chloroacetate (22524-32-9) + 1-phenylbiguanide (102-02-3) → 6-(bromo-chloro-methyl)-N2-phenyl-[1,3,5]triazine-2,4-diyldiamine (98946-68-0)

Guidance literature:

With sodium methylate;

DOI:10.1021/ja01561a044

upstream raw materials:

acetic acid

benzoic acid

Downstream raw materials:

bromochloroacetamide

6-(bromo-chloro-methyl)-N²-phenyl-[1,3,5]triazine-2,4-diyldiamine