2-Chloro-5-trifluoromethylbenzyl chloride

Base Information

Chemical Name:2-Chloro-5-trifluoromethylbenzyl chloride
CAS No.:22902-87-0
Molecular Formula:C8H5Cl2F3
Molecular Weight:229.029
Hs Code.:2903999090
European Community (EC) Number:675-116-3
DSSTox Substance ID:DTXSID50374081
Wikidata:Q82162562
Mol file:22902-87-0.mol

Synonyms:2-Chloro-5-trifluoromethylbenzyl chloride;22902-87-0;2-Chloro-5-(trifluoromethyl)benzyl chloride;1-chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene;2-CHLORO-5-TRIFLUOROMETHYLBENZYLCHLORIDE;SCHEMBL5436712;DTXSID50374081;MFCD04972760;AKOS005216785;FS-3975;FT-0764881;EN300-338468;2-chloro-5-trifluoromethylbenzyl chloride, AldrichCPR

Suppliers and Price of 2-Chloro-5-trifluoromethylbenzyl chloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-CHLORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE 95.00%
5MG
$ 504.16

AK Scientific
2-Chloro-5-trifluoromethylbenzylchloride
100g
$ 785.00

AK Scientific
2-Chloro-5-trifluoromethylbenzylchloride
5g
$ 120.00

Total 7 raw suppliers

Chemical Property of 2-Chloro-5-trifluoromethylbenzyl chloride

Chemical Property:

PSA：0.00000
LogP:4.09760
XLogP3:3.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:227.9720400
Heavy Atom Count:13
Complexity:169

Purity/Quality:

99% ^*data from raw suppliers

2-CHLORO-5-TRIFLUOROMETHYLBENZYL CHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1C(F)(F)F)CCl)Cl

Technology Process of 2-Chloro-5-trifluoromethylbenzyl chloride

There total 5 articles about 2-Chloro-5-trifluoromethylbenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 64372-62-9
(2-chloro-5-(trifluoromethyl)phenyl)methanol

: 22902-87-0
1-chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene

Guidance literature:: With thionyl chloride; In N,N-dimethyl-formamide; at 0 ℃; for 1h;
DOI:10.1002/jlcr.3073

Reference yield: 82.4%

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 98-56-6
4-chlorobenzotrifluoride

: 22902-87-0
1-chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene

Guidance literature:: With hydrogenchloride; zinc(II) chloride; at 25 - 40 ℃; for 2h; Reagent/catalyst; Concentration; Cooling with ice;

Reference yield:

: 82386-89-8
2-chloro-5-(trifluoromethyl)benzaldehyde

: 22902-87-0
1-chloro-2-(chloromethyl)-4-(trifluoromethyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / NaBH₄ / dioxane; H₂O / 0.5 h / 30 - 40 °C

2: 86 percent / SOCl₂ / CHCl₃; pyridine / 48 h / 10 - 20 °C

With sodium tetrahydroborate; thionyl chloride; In 1,4-dioxane; pyridine; chloroform; water;
DOI:10.1135/cccc19820967