1-(4-Iodophenyl)-2-methylpropan-2-amine

Base Information

Chemical Name:1-(4-Iodophenyl)-2-methylpropan-2-amine
CAS No.:96684-29-6
Molecular Formula:C10H14 I N
Molecular Weight:275.13
Hs Code.:2921499090
DSSTox Substance ID:DTXSID00242387
Wikidata:Q83126069
Mol file:96684-29-6.mol

Synonyms:4-iodo-alpha,alpha-dimethylphenethylamine;4-iodophentermine;4-iodophentermine, 123I-labeled;4-iodophentermine, 125I-labeled;4-iodophentermine, 131I-labeled;p-iodophentermine

Suppliers and Price of 1-(4-Iodophenyl)-2-methylpropan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-(4-Iodophenyl)-2-methylpropan-2-amine

Chemical Property:

Vapor Pressure:0.00272mmHg at 25°C
Boiling Point:285.9°C at 760 mmHg
Flash Point:126.7°C
PSA：26.02000
Density:1.519g/cm³
LogP:3.27130
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:275.01710
Heavy Atom Count:12
Complexity:137

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(CC1=CC=C(C=C1)I)N

Technology Process of 1-(4-Iodophenyl)-2-methylpropan-2-amine

There total 4 articles about 1-(4-Iodophenyl)-2-methylpropan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 7285-11-2
chloroform methanol

: 7664-93-9
sulfuric acid

: 51131-55-6
4-(β-amino-isobutyl)-aniline

: 96684-29-6
2-amino-2-methyl-1-(4-iodophenyl)propane

Guidance literature:: With sodium iodide; sodium nitrite; In water;

Reference yield:

: 1197-21-3
phentermine hydrochloride

: 96684-29-6
2-amino-2-methyl-1-(4-iodophenyl)propane

Guidance literature:: Multi-step reaction with 3 steps

1: 56 percent / conc. H₂SO₄, 70percent aq. HNO₃ / 0.33 h

2: 3.87 g / NaOH, hydrazine, Raney nickel / ethanol / 0.33 h / 40 °C

3: 1.) 5percent aq. H₂SO₄, NaNO₂, 2.) NaI / 1.) 30 min, 2.) 30 min

With sodium hydroxide; sulfuric acid; nitric acid; nickel; sodium iodide; hydrazine; sodium nitrite; In ethanol;
DOI:10.1021/jm00392a006

Reference yield:

: 108835-36-5
2-amino-2-methyl-1-(4-nitrophenyl)propane sulfate

: 96684-29-6
2-amino-2-methyl-1-(4-iodophenyl)propane

Guidance literature:: Multi-step reaction with 2 steps

1: 3.87 g / NaOH, hydrazine, Raney nickel / ethanol / 0.33 h / 40 °C

2: 1.) 5percent aq. H₂SO₄, NaNO₂, 2.) NaI / 1.) 30 min, 2.) 30 min

With sodium hydroxide; sulfuric acid; nickel; sodium iodide; hydrazine; sodium nitrite; In ethanol;
DOI:10.1021/jm00392a006