4-fluoro-N-(2-oxo-2-phenylethyl)benzamide

Base Information

Chemical Name:4-fluoro-N-(2-oxo-2-phenylethyl)benzamide
CAS No.:2368-16-3
Molecular Formula:C15H12FNO2
Molecular Weight:257.264
Hs Code.:2924299090
DSSTox Substance ID:DTXSID90355293
Nikkaji Number:J3.661.253C
Wikidata:Q82134087
ChEMBL ID:CHEMBL1371961
Mol file:2368-16-3.mol

Synonyms:4-fluoro-N-(2-oxo-2-phenylethyl)benzamide;4-fluoro-N-phenacylbenzamide;2368-16-3;Cambridge id 5337912;Oprea1_665493;Oprea1_823571;MLS001203319;CHEMBL1371961;SCHEMBL23014282;DTXSID90355293;HMS2823I04;STK330002;AKOS000581246;SMR000515230;4-Fluoro-N-(2-oxo-2-phenyl-ethyl)-benzamide;AK-968/11738227

Suppliers and Price of 4-fluoro-N-(2-oxo-2-phenylethyl)benzamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-fluoro-N-(2-oxo-2-phenylethyl)benzamide

Chemical Property:

Vapor Pressure:1.93E-08mmHg at 25°C
Melting Point:138-139 °C(Solv: ethyl acetate (141-78-6))
Boiling Point:454.3oC at 760 mmHg
PKA:12.97±0.46(Predicted)
Flash Point:228.5oC
PSA：46.17000
Density:1.225g/cm3
LogP:2.82930
XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:257.08520679
Heavy Atom Count:19
Complexity:318

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)CNC(=O)C2=CC=C(C=C2)F

Technology Process of 4-fluoro-N-(2-oxo-2-phenylethyl)benzamide

There total 7 articles about 4-fluoro-N-(2-oxo-2-phenylethyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1590389-14-2
potassium trifluoro(4-fluorobenzoyl)borate

: 5468-37-1
2-aminoacetophenone hydrochloride

: 2368-16-3
4-Fluoro-N-[1-(2-oxo-2-phenylethyl)]benzamide

Guidance literature:: With 1,3-dichloro-5,5-dimethylhydantoin; In tetrahydrofuran; at 20 ℃; for 1.5h; pH=3; chemoselective reaction;
DOI:10.1021/jacs.7b00059

Reference yield: 94.0%

: C₁₅H₁₁BF₄NO^(1-)*H⁽¹⁺⁾

: 2368-16-3
4-Fluoro-N-[1-(2-oxo-2-phenylethyl)]benzamide

Guidance literature:: With dihydrogen peroxide; N-ethyl-N,N-diisopropylamine; In water; acetonitrile; at 20 ℃; for 0.5h;
DOI:10.1039/d0sc01330g