3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide

Base Information

Chemical Name:3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide
CAS No.:23784-70-5
Molecular Formula:C11H12ClNO
Molecular Weight:209.675
Hs Code.:
DSSTox Substance ID:DTXSID00392472
Mol file:23784-70-5.mol

Synonyms:3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide;23784-70-5;SCHEMBL3413340;DTXSID00392472;AKOS034179174

Suppliers and Price of 3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide

Chemical Property:

XLogP3:2.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:2
Exact Mass:209.0607417
Heavy Atom Count:14
Complexity:217

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN(C)C(=O)C=CC1=CC=C(C=C1)Cl

Technology Process of 3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide

There total 4 articles about 3-(4-chlorophenyl)-N,N-dimethylprop-2-enamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 127-19-5,116057-81-9
N,N-dimethyl acetamide

: 104-88-1
4-chlorobenzaldehyde

: 23784-70-5
1-(4-chloro-phenyl)-3-dimethylamino-propenone

Guidance literature:: With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; Inert atmosphere; Schlenk technique;
DOI:10.1039/c8dt05020a

Reference yield: 45.0%

: 873-73-4
4-n-chlorophenylacetylene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 1207958-16-4
2-(4-chlorophenyl)-N,N-dimethylacrylamide

: 23784-70-5
1-(4-chloro-phenyl)-3-dimethylamino-propenone

Guidance literature:: With bis(benzonitrile)palladium(II) dichloride; benzoyl chloride; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,3,5-trimethyl-benzene; at 140 ℃; for 20h; regioselective reaction; Inert atmosphere;
DOI:10.1021/ja910038p

Reference yield:

: 1615-02-7,940-62-5
p-chlorocinnamic acid

: 124-40-3
dimethyl amine

: 23784-70-5
1-(4-chloro-phenyl)-3-dimethylamino-propenone

Guidance literature:: With dmap; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In dichloromethane; at 0 - 20 ℃; for 3h;
DOI:10.1021/jacs.0c09654