9-(2-Pyridyl)carbazole

Base Information

• Chemical Name: 9-(2-Pyridyl)carbazole
• CAS No.: 23866-67-3
• Molecular Formula: C17H12N2
• Molecular Weight: 244.29100
• DSSTox Substance ID: DTXSID50435540
• Nikkaji Number: J2.107.417I
• Wikidata: Q82250559
• Mol file: 23866-67-3.mol

Synonyms:9-(2-pyridyl)carbazole;23866-67-3;9-(pyridin-2-yl)-9H-carbazole;9-(2-Pyridyl)-9H-carbazole;2-(9-carbazolyl-)pyridin;2-(9-Carbazolyl)-pyridin;SCHEMBL730611;9-(2-pyridinyl)-9H-carbazole;DTXSID50435540;JDINBEDUGBFLEC-UHFFFAOYSA-N;MFCD18431639;SY264808

Chemical Property of 9-(2-Pyridyl)carbazole

Chemical Property:

• PSA: 17.82000
• LogP: 4.17870
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 244.100048391
• Heavy Atom Count: 19
• Complexity: 294

Purity/Quality:

98% ^*data from raw suppliers

9-(2-Pyridyl)carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C3=CC=CC=C3N2C4=CC=CC=N4

Technology Process of 9-(2-Pyridyl)carbazole

There total 29 articles about 9-(2-Pyridyl)carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-iodopyridine (5029-67-4) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 9-(2-pyridyl)carbazole (23866-67-3)

Guidance literature:

With copper(I) oxide; potassium phosphate; N¹,N²-bis(furan-2-ylmethyl)oxalamide; In acetonitrile; at 80 ℃;

DOI:10.1002/adsc.201700026

Reference yield: 99.0%

(N-([1,1′-biphenyl]-2-yl)pyridin-2-amine) (1256380-82-1) → 9-(2-pyridyl)carbazole (23866-67-3)

Guidance literature:

With silver(I) acetate; palladium diacetate; In 1,4-dioxane; at 140 ℃; for 1h;

DOI:10.1002/chem.201101528

Reference yield: 98.0%

2-bromo-pyridine (109-04-6) + 9H-carbazole (86-74-8,105184-46-1,97960-57-1) → 9-(2-pyridyl)carbazole (23866-67-3)

Guidance literature:

With copper(I) oxide; potassium phosphate; N¹,N²-bis(furan-2-ylmethyl)oxalamide; In dimethyl sulfoxide; at 120 ℃; for 36h;

DOI:10.1002/adsc.201700026

upstream raw materials:

2-bromo-pyridine

9H-carbazole

2-fluoropyridine

sodium salt of carbazole

Refernces

• 1、 Maiti, Subhadip,Mandal, Tirtha,Dash, Barada Prasanna,Dash, Jyotirmayee. "Site-Selective Aerobic C-H Monoacylation of Carbazoles Using Palladium Catalysis". . p. 1396 - 1407. Retrieved 2021.
• 2、 Zhao, Xiangdong,She, Yuanbin,Fang, Kun,Li, Guijie. "CuCl-Catalyzed Ullmann-Type C-N Cross-Coupling Reaction of Carbazoles and 2-Bromopyridine Derivatives". . p. 1024 - 1033. Retrieved 2017.
• 3、 Thamilarasan,Jayamani,Manisankar,Kim, Young-Inn,Sengottuvelan. "Green-emitting phosphorescent iridium(III) complex: Structural, photophysical and electrochemical properties". . p. 240 - 245. Retrieved 2013.
• 4、 Li, Dong-Hui,Lan, Xiao-Bing,Song, A-Xiang,Rahman, Md. Mahbubur,Xu, Chang,Huang, Fei-Dong,Szostak, Roman,Szostak, Michal,Liu, Feng-Shou. "Buchwald-Hartwig Amination of Coordinating Heterocycles Enabled by Large-but-Flexible Pd-BIAN-NHC Catalysts**". supporting information. . Retrieved 2021/12/06.