(S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate

Base Information

Chemical Name:(S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate
CAS No.:24277-38-1
Molecular Formula:C15H27NO6
Molecular Weight:317.382
Hs Code.:
Mol file:24277-38-1.mol

Synonyms:α-tert-butyl γ-methyl N-Boc-L-glutamate;(S)-(-)-1-tert-butyl-5-methyl-[(2-tert-butoxycarbonyl)amino]pentanedioate;Boc-Glu(OMe)-OtBu;1-tert-butyl 5-methyl (2S)-2-{[(tert-butoxy)carbonyl]amino}pentanedioate;α-tert-butyl γ-methyl N-(tert-butoxycarbonyl)-L-glutamate;

Suppliers and Price of (S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
N-Boc 1-O-t-Butyl 5-O-Methoxy L-Glutamic Acid
10mg
$ 502.00

TRC
N-Boc1-O-t-Butyl5-O-MethoxyL-GlutamicAcid
25mg
$ 420.00

Total 12 raw suppliers

Chemical Property of (S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate

Chemical Property:

Melting Point:65-67 °C(Solv: ethanol, 50% (64-17-5))
Boiling Point:403.1±35.0 °C(Predicted)
PKA:10.86±0.46(Predicted)
PSA：90.93000
Density:1.072±0.06 g/cm3(Predicted)
LogP:2.56550
Storage Temp.:-20°C Freezer
Solubility.:Chloroform, DCM

Purity/Quality:

99%, ^*data from raw suppliers

N-Boc 1-O-t-Butyl 5-O-Methoxy L-Glutamic Acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses N-Boc 1-O-t-Butyl 5-O-Methoxy L-Glutamic Acid is an intermediate used in the synthesis of Isodesmosine Chloride Hydrate (Synthetic) (I815051), which is a component of elastin and also it is extremely hygroscopic and must be stored over a desiccant such as silica gel.

Technology Process of (S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate

There total 1 articles about (S)-1-tert-Butyl 5-methyl 2-((tert-butoxycarbonyl)amino)pentanedioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

: 91229-91-3
tert-butyl (S)-N-tert-butoxycarbonylpyroglutamate

: 79-22-1
methyl chloroformate

: 24277-38-1
(S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate

Guidance literature:: tert-butyl (S)-N-tert-butoxycarbonylpyroglutamate; With lithium hydroxide; In tetrahydrofuran; at 0 ℃;

methyl chloroformate; With dmap; triethylamine; In dichloromethane; at 0 ℃; Further stages.;
DOI:10.1016/j.tetlet.2004.02.118

Reference yield: 84.0%

: 24277-38-1
(S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate

: 24277-39-2
N-tert-butoxycarbonyl glutamic acid tert-butyl ester

Guidance literature:: With lithium hydroxide; In tetrahydrofuran; water;
DOI:10.1016/j.bmcl.2006.12.056

Reference yield: 81.0%

: 100-39-0
benzyl bromide

: 24277-38-1
(S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate

: 528588-35-4
2-benzyl-4-tert-butoxycarbonylamino-pentanedioic acid 5-tert-butyl ester 1-methyl ester

Guidance literature:: (S)-(-)-1-tert-butyl-5-methyl-<(2-tert-butoxycarbonyl)amino>pentanedioate; With lithium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 0.5h;

benzyl bromide; In tetrahydrofuran;
DOI:10.1016/S0040-4039(02)02865-4