1-bromo-2,3-dihydro-1H-indene

Base Information

• Chemical Name: 1-bromo-2,3-dihydro-1H-indene
• CAS No.: 24373-98-6
• Molecular Formula: C9H9Br
• Molecular Weight: 197.074
• European Community (EC) Number: 815-397-3
• DSSTox Substance ID: DTXSID30450054
• Nikkaji Number: J380.285J
• Mol file: 24373-98-6.mol

Synonyms:1-bromo-2,3-dihydro-1H-indene;1-Bromoindan;24373-98-6;1H-Indene, 1-bromo-2,3-dihydro-;bromoindane;1-bromo-indan;SCHEMBL1973082;DTXSID30450054;BVMGTUJYIOYCBX-UHFFFAOYSA-N;AKOS009308409;EN300-156630

Chemical Property of 1-bromo-2,3-dihydro-1H-indene

Chemical Property:

• Boiling Point: 235.9±19.0 °C(Predicted)
• PSA: 0.00000
• Density: 1.483±0.06 g/cm3(Predicted)
• LogP: 3.06880
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 195.98876
• Heavy Atom Count: 10
• Complexity: 122

Purity/Quality:

1-Bromo-2,3-dihydro-1H-indene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CC2=CC=CC=C2C1Br

Technology Process of 1-bromo-2,3-dihydro-1H-indene

There total 2 articles about 1-bromo-2,3-dihydro-1H-indene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.6%

INDANE (496-11-7) → 2-bromoindane (17623-96-0) + 1-bromoindane (24373-98-6)

Guidance literature:

With styrene-4-vinyl(N-alkylpyridinium bromide); In water; acetic acid; at 23 ℃; for 24h;

DOI:10.1016/S0040-4020(01)85800-2

Reference yield:

1-Indanol (6351-10-6) → 1-bromoindane (24373-98-6) + 1-indene (95-13-6)

Guidance literature:

With pyridine; phosphorus tribromide; In dichloromethane; at -10 ℃; for 0.5h; Title compound not separated from byproducts;

DOI:10.1021/ja053751f

Reference yield: 75.0%

trans-2-phenylvinylboronic acid (6783-05-7) + 1-bromoindane (24373-98-6) → (E)-1-styryl-2,3-dihydro-1H-indene

Guidance literature:

With potassium phosphate; In toluene; at 80 ℃; for 4h; stereospecific reaction; Inert atmosphere;

DOI:10.1021/jacs.6b06285

upstream raw materials:

INDANE

1-Indanol

Downstream raw materials:

indan-1-yl-o-tolyl-amine

1-(benzyloxy)-2,3-dihydro-1H-indene

1-indanyl-hydrazine

C₁₆H₁₃N₃