1-(4-Phenyl-1,3-thiazol-2-yl)guanidine

Base Information

Chemical Name:1-(4-Phenyl-1,3-thiazol-2-yl)guanidine
CAS No.:2507-81-5
Molecular Formula:C10H10N4S
Molecular Weight:218.282
Hs Code.:
DSSTox Substance ID:DTXSID70396088
Nikkaji Number:J276.538A
ChEMBL ID:CHEMBL145703
Mol file:2507-81-5.mol

Synonyms:2507-81-5;N-(4-phenyl-1,3-thiazol-2-yl)guanidine;1-(4-phenyl-1,3-thiazol-2-yl)guanidine;1-(4-Phenylthiazol-2-yl)guanidine;2-(4-phenyl-1,3-thiazol-2-yl)guanidine;CHEMBL145703;N-(4-Phenyl-thiazol-2-yl)-guanidine;N''-(4-phenyl-1,3-thiazol-2-yl)guanidine;2-guanidino-4-phenylthiazole;SCHEMBL823907;DTXSID70396088;GENKQMMVXFFZPC-UHFFFAOYSA-N;CAA50781;2-(4-Phenylthiazole-2-yl)guanidine;BBL012925;BDBM50013293;MFCD03617546;MFCD06739728;STK292365;AKOS002336050;AKOS015993059;N -(4-Phenyl-thiazol-2-yl)-guanidine;CS-0323865;5T-0918

Suppliers and Price of 1-(4-Phenyl-1,3-thiazol-2-yl)guanidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
N-(4-Phenyl-1,3-thiazol-2-yl)guanidine
500mg
$ 315.00

Crysdot
1-(4-Phenylthiazol-2-yl)guanidine 97%
1g
$ 450.00

Total 7 raw suppliers

Chemical Property of 1-(4-Phenyl-1,3-thiazol-2-yl)guanidine

Chemical Property:

Boiling Point:401.6±38.0 °C(Predicted)
PKA:8.49±0.70(Predicted)
PSA：103.03000
Density:1.41±0.1 g/cm3(Predicted)
LogP:2.98850
XLogP3:1.8
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:218.06261751
Heavy Atom Count:15
Complexity:234

Purity/Quality:

98%min ^*data from raw suppliers

N-(4-Phenyl-1,3-thiazol-2-yl)guanidine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=CSC(=N2)N=C(N)N

Technology Process of 1-(4-Phenyl-1,3-thiazol-2-yl)guanidine

There total 2 articles about 1-(4-Phenyl-1,3-thiazol-2-yl)guanidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 98-86-2
acetophenone

: 2507-81-5
N-(4-phenyl-1,3-thiazol-2-yl)guanidine

Guidance literature:: With Oxone; sodium bromide; In methanol; at 60 ℃; for 2h;

Reference yield: 78.0%

: 2114-02-5
amidinothiocarbamide

: 70-11-1
α-bromoacetophenone

: 2507-81-5
1-(4-phenylthiazol-2-yl)guanidine

Guidance literature:: In ethanol; for 2h; Reflux;
DOI:10.1039/d1nj01943k

Reference yield: 92.0%

: 766-81-4
3-bromophenylacetylene

: 2507-81-5
1-(4-phenylthiazol-2-yl)guanidine

: 3-bromo-N-(N-(4-phenylthiazol-2-yl)carbamimidoyl)benzimidamide

Guidance literature:: 1-(4-phenylthiazol-2-yl)guanidine; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 - 20 ℃; for 0.5h;

3-bromophenylacetylene; In N,N-dimethyl-formamide; mineral oil; at 20 ℃;
DOI:10.1039/d1nj01943k