(E)-2,6-Dichlorostilbene

Base Information

• Chemical Name: (E)-2,6-Dichlorostilbene
• CAS No.: 25144-42-7
• Molecular Formula: C14H10Cl2
• Molecular Weight: 249.14
• Mol file: 25144-42-7.mol

Synonyms:

Chemical Property of (E)-2,6-Dichlorostilbene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-2,6-Dichlorostilbene

There total 14 articles about (E)-2,6-Dichlorostilbene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

2,6-dichlorostyrene (28469-92-3) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → (E)-1,3-dichloro-2-styrylbenzene (25144-42-7)

Guidance literature:

With diisopropylsulfide; palladium diacetate; silver carbonate; Trimethylacetic acid; at 120 ℃; for 8h; Inert atmosphere;

DOI:10.1039/c2cc33100d

Reference yield:

N'-(2,6-dichlorobenzylidene)-4-methylbenzene-1-sulfonohydrazide (37532-04-0) + benzyl chloride (100-44-7) → (Z)-1,3-dichloro-2-styrylbenzene (76089-72-0,25144-42-7) + (E)-1,3-dichloro-2-styrylbenzene (25144-42-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium tert-butoxide; In toluene; at 80 ℃; for 6h; stereoselective reaction;

DOI:10.2174/1570178615666171222163927

Reference yield:

N'-(2,6-dichlorobenzylidene)-4-methylbenzene-1-sulfonohydrazide (37532-04-0) + benzyl chloride (100-44-7) → (Z)-1,3-dichloro-2-styrylbenzene (76089-72-0,25144-42-7) + (E)-1,3-dichloro-2-styrylbenzene (25144-42-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; lithium tert-butoxide; In toluene; at 80 ℃; for 6h; stereoselective reaction;

DOI:10.2174/1570178615666171222163927

upstream raw materials:

benzyltriphenylphosphonium bromide

2,6-dichlorobenzaldehyde

N'-(2,6-dichlorobenzylidene)-4-methylbenzene-1-sulfonohydrazide

benzyl bromide

Downstream raw materials:

C₁₄H₈Cl₂O₂

Refernces

• 1、 -. "THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS". Page/Page column 36; 48-49. . Retrieved 2015/06/18.
• 2、 -. "Substituted CIS- and trans-stilbenes as therapeutic agents". Page/Page column 20. . Retrieved 2010/11/28.