Pyridinium, 4-methyl-, 2-oxo-2-phenylethylide

Base Information

• Chemical Name: Pyridinium, 4-methyl-, 2-oxo-2-phenylethylide
• CAS No.: 25357-50-0
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.263
• Mol file: 25357-50-0.mol

Synonyms:

Chemical Property of Pyridinium, 4-methyl-, 2-oxo-2-phenylethylide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Pyridinium, 4-methyl-, 2-oxo-2-phenylethylide

There total 3 articles about Pyridinium, 4-methyl-, 2-oxo-2-phenylethylide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-methyl-1-(2-oxo-2-phenylethyl)pyridinium bromide (7250-28-4) → 4-methylpyridinium phenacylide (25357-50-0)

Guidance literature:

With 1-methyl-2,3,4,6,7,8-hexahydro-1H-pyrimido[1,2-a]pyrimidine; In dimethyl sulfoxide; at 30 - 50 ℃; Kinetics; Activation energy;

DOI:10.1016/S0022-2860(00)00585-8

Reference yield:

picoline (108-89-4) + α-bromoacetophenone (70-11-1) → 4-methylpyridinium phenacylide (25357-50-0)

Guidance literature:

Multi-step reaction with 2 steps

1: acetonitrile / Reflux

2: potassium carbonate / water

With potassium carbonate; In water; acetonitrile;

DOI:10.1021/om201001c

Reference yield:

→ 4-methylpyridinium phenacylide (25357-50-0)

Guidance literature:

N-Phenacyl-4-methylpyridiniumbromid, Na2CO3;

upstream raw materials:

4-methyl-1-(2-oxo-2-phenylethyl)pyridinium bromide

picoline

α-bromoacetophenone

Downstream raw materials:

W(CO)5C₆H₅COCHNC₅H₄CH₃

(3aS,4S,9aR,9bR)-4-Benzoyl-8-methyl-2-p-tolyl-3a,4,9a,9b-tetrahydro-pyrrolo[3,4-a]indolizine-1,3-dione

3-[2-Oxo-2-phenyl-eth-(E)-ylidene]-1-p-tolyl-pyrrolidine-2,5-dione

Refernces

• 1、 Dega-Szafran,Schroeder,Szafran,Szwajca,L?ska,Lewandowska. "Experimental and quantum chemical evidences for C-H···N hydrogen bonds involving quaternary pyridinium salts and pyridinium ylides". . p. 31 - 42. Retrieved 2007/10/03.