93199-59-8Relevant academic research and scientific papers
Synthesis and Anticancer Activity of 1,2,3-Triazole Fused N-Arylpyrazole Derivatives
Lakkakula,Roy,Mukkanti,Sridhar
, p. 831 - 835 (2019)
A novel series of triazole derivatives 11a–11j is synthesized. Structures of the products are confirmed by 1H and 13C NMR, and mass spectral data. The anticancer activities of compounds 11a–11j are evaluated against three human cance
Synthesis of dibenzoylmethane derivatives and inhibition of mutagenicity in Salmonella typhimurium
Choshi,horimoto,Wang,Nagase,Ichikawa,Sugino,Hibino
, p. 1047 - 1049 (2007/10/02)
Twenty dibenzoylmethanes with methyl, methoxy, bromo, chloro, or fluoro substitution on either one or both benzene rings were synthesized and assayed for inhibition of the mutagenicity of 2-nitrofluorene in S. typhimurium TA98. 2,2-Dimethoxy, 3,3-dimethoxy and 3,3,4,4-tetramethoxydibenzoylmethane was as active as dibenzoylmethane. None of the halogen-substituted dibenzoylmethanes were active. These results demonstrate that dibenzoylmethanes can inhibit the mutagenicity of 2-nitrofluorene, and that modifications made on the benzene rings of dibenzoylmethane cannot enhance the antimutagenicity of this parent compound.
