[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid

Base Information

Chemical Name:[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid
CAS No.:255874-78-3
Molecular Formula:C12H9ClN2O3S
Molecular Weight:296.734
Hs Code.:2934100090
DSSTox Substance ID:DTXSID40350359
Wikidata:Q82126251
ChEMBL ID:CHEMBL4741321
Mol file:255874-78-3.mol

Synonyms:255874-78-3;[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid;2-[2-[(4-chlorobenzoyl)amino]-1,3-thiazol-4-yl]acetic Acid;2-(2-(4-chlorobenzamido)thiazol-4-yl)acetic acid;{2-[(4-chlorobenzoyl)amino]-1,3-thiazol-4-yl}acetic acid;2-[2-[(4-Chlorobenzoyl)amino)-1,3-thiazol-4-yl]acetic acid;Oprea1_100331;SCHEMBL3544268;CHEMBL4741321;DTXSID40350359;DDKSZHVERDDFMO-UHFFFAOYSA-N;MFCD00829319;AKOS000128467;BB 0218032;CS-0117011;EN300-235990;2-(2-(4-chlorobenzamido)thiazol-4-yl)aceticacid;2-[2-(4-chlorobenzamido)-1,3-thiazol-4-yl]acetic acid;F2158-0335

Suppliers and Price of [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid
1g
$ 378.00

Crysdot
2-(2-(4-Chlorobenzamido)thiazol-4-yl)aceticacid 97%
5g
$ 701.00

American Custom Chemicals Corporation
[2-(4-CHLORO-BENZOYLAMINO)-THIAZOL-4-YL]-ACETIC ACID 95.00%
1G
$ 672.00

AK Scientific
[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-aceticacid
1g
$ 560.00

Total 5 raw suppliers

Chemical Property of [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid

Chemical Property:

PSA：107.53000
LogP:2.74890
XLogP3:2.2
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:296.0022410
Heavy Atom Count:19
Complexity:348

Purity/Quality:

98%min ^*data from raw suppliers

[2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=CC=C1C(=O)NC2=NC(=CS2)CC(=O)O)Cl

Technology Process of [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid

There total 3 articles about [2-(4-Chloro-benzoylamino)-thiazol-4-yl]-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 329699-54-9
2-[[(4-chlorophenyl)carbonyl]amino]-1,3-thiazol-4-yl-acetic acid ethyl ester

: 255874-78-3
2-(4-chlorobenzamido)thiazol-4-acetic acid

Guidance literature:: 2-[[(4-chlorophenyl)carbonyl]amino]-1,3-thiazol-4-yl-acetic acid ethyl ester; With sodium hydroxide; ethanol; water; at 20 ℃; for 2 - 24h;

With hydrogenchloride; In diethyl ether;

Reference yield:

: 53266-94-7
ethyl 2-amino-1,3-thiazol-4-acetate

: 255874-78-3
2-(4-chlorobenzamido)thiazol-4-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine / tetrahydrofuran / 12 h / 20 °C

2: sodium hydroxide / ethanol; water / 0.5 h / Reflux

With 4-methyl-morpholine; sodium hydroxide; In tetrahydrofuran; ethanol; water;
DOI:10.1016/j.cclet.2015.09.008

Reference yield:

: 122-01-0
4-chloro-benzoyl chloride

: 255874-78-3
2-(4-chlorobenzamido)thiazol-4-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 4-methyl-morpholine / tetrahydrofuran / 12 h / 20 °C

2: sodium hydroxide / ethanol; water / 0.5 h / Reflux

With 4-methyl-morpholine; sodium hydroxide; In tetrahydrofuran; ethanol; water;
DOI:10.1016/j.cclet.2015.09.008