3-Hydroxy-4-nitrobenzyl bromide

Base Information

Chemical Name:3-Hydroxy-4-nitrobenzyl bromide
CAS No.:26386-82-3
Molecular Formula:C7H6BrNO3
Molecular Weight:232.034
Hs Code.:
DSSTox Substance ID:DTXSID90452650
Nikkaji Number:J886.614G

Synonyms:26386-82-3;3-HYDROXY-4-NITROBENZYL BROMIDE;5-(BROMOMETHYL)-2-NITROPHENOL;Phenol, 5-(bromomethyl)-2-nitro-;2-Nitro-5-(bromomethyl)phenol;SCHEMBL8063487;DTXSID90452650;AB72527;EN300-1896258

Suppliers and Price of 3-Hydroxy-4-nitrobenzyl bromide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 3-Hydroxy-4-nitrobenzyl bromide

Chemical Property:

XLogP3:2.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:230.95311
Heavy Atom Count:12
Complexity:171

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CBr)O)[N+](=O)[O-]

Technology Process of 3-Hydroxy-4-nitrobenzyl bromide

There total 3 articles about 3-Hydroxy-4-nitrobenzyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 61161-83-9
5-(hydroxymethyl)-2-nitrophenol

: 26386-82-3
5-(bromomethyl)-2-nitrophenol

Guidance literature:: With carbon tetrabromide; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 16h;

Reference yield:

: 704-13-2
5-formyl-2-nitrophenol

: 26386-82-3
5-(bromomethyl)-2-nitrophenol

Guidance literature:: Multi-step reaction with 2 steps

1: 97 percent / NaBH₄ / methanol; tetrahydrofuran; diethyl ether / 0 deg C, 30 min, 0 deg C to rt, 2 h

2: 86 percent / CBr₄, PPh₃ / CH₂Cl₂ / 0 deg C, 30 min, 0 deg C to rt

With sodium tetrahydroborate; carbon tetrabromide; triphenylphosphine; In tetrahydrofuran; methanol; diethyl ether; dichloromethane;
DOI:10.1021/ja964366g

Reference yield:

: 619-14-7
3-hydroxy-4-nitro-benzoic acid

: 26386-82-3
5-(bromomethyl)-2-nitrophenol

Guidance literature:: Multi-step reaction with 2 steps

1: Trimethyl borate; boron trifluoride diethyl etherate; borane pyridine; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / 3 h / 20 °C

2: carbon tetrabromide; triphenylphosphine / dichloromethane / 3 h / 0 - 20 °C

With borane pyridine; Trimethyl borate; carbon tetrabromide; boron trifluoride diethyl etherate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triphenylphosphine; In dichloromethane;
DOI:10.1016/j.jphotochem.2014.02.013