5,6-Diphenyl-2,3-dihydropyrazine

Base Information

• Chemical Name: 5,6-Diphenyl-2,3-dihydropyrazine
• CAS No.: 1489-06-1
• Molecular Formula: C16H14 N2
• Molecular Weight: 234.301
• Hs Code.: 2933990090
• NSC Number: 82696
• DSSTox Substance ID: DTXSID70292450
• Nikkaji Number: J1.416.585A
• Wikidata: Q82030755
• Mol file: 1489-06-1.mol

Synonyms:5,6-diphenyl-2,3-dihydropyrazine;1489-06-1;2,3-diphenyl-5,6-dihydropyrazine;NSC82696;Pyrazine,2,3-dihydro-5,6-diphenyl-;2,3-DIHYDRO-5,6-DIPHENYLPYRAZINE;Maybridge1_007448;SCHEMBL2282129;HMS562K12;DTXSID70292450;5,6-Diphenyl2,3-dihydropyrazine;RKLPQDGVFVQQOT-UHFFFAOYSA-N;CCG-51053;MFCD00047388;NSC-82696;STK687785;AKOS002378495;CS-0334037;FT-0619835;SR-01000640379-1

Chemical Property of 5,6-Diphenyl-2,3-dihydropyrazine

Chemical Property:

• Vapor Pressure: 1.01E-05mmHg at 25°C
• Melting Point: 160 °C
• Boiling Point: 382.9°Cat760mmHg
• Flash Point: 177.7°C
• PSA: 24.72000
• Density: 1.09g/cm³
• LogP: 1.84980
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 234.115698455
• Heavy Atom Count: 18
• Complexity: 297

Purity/Quality:

98%min ^*data from raw suppliers

5,6-Diphenyl-2,3-dihydropyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CN=C(C(=N1)C2=CC=CC=C2)C3=CC=CC=C3

Technology Process of 5,6-Diphenyl-2,3-dihydropyrazine

There total 11 articles about 5,6-Diphenyl-2,3-dihydropyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

ethylenediamine (107-15-3,85404-18-8) + benzil (134-81-6) → 2,3-diphenyl-5,6-dihydropyrazine (1489-06-1)

Guidance literature:

With amberlyst-15; In water; at 70 ℃; for 0.25h;

DOI:10.1080/00397910903219401

Reference yield: 99.0%

2-hydroxy-2-phenylacetophenone (119-53-9,579-44-2) + ethylenediamine (107-15-3,85404-18-8) → 2,3-diphenyl-5,6-dihydropyrazine (1489-06-1)

Guidance literature:

With morpholine; iron(III) chloride; In ethanol; at 80 ℃; for 0.3h;

DOI:10.1080/00397911.2010.523489

Reference yield: 90.0%

2,3-butane diamine (563-86-0) + benzil (134-81-6) → 2,3-diphenyl-5,6-dihydropyrazine (1489-06-1)

Guidance literature:

In neat (no solvent); at 20 ℃; for 0.166667h; Green chemistry;

DOI:10.4067/S0717-97072015000100017

upstream raw materials:

ethylenediamine

benzil

N,N`-dimethylethylenediamine

1,2-di(4-methylphenyl)-1,2-ethanedione

Downstream raw materials:

2,3-diphenyl-piperazine-2,3-dicarbonitrile

2,3-diphenylpyrazine

5,6-diphenyl-2,3-dihydro-pyrazine-1,4-dioxide

1,4-diacetyl-2,3-diphenyl-1,4,5,6-tetrahydropyrazine