(S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate

Base Information

Chemical Name:(S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate
CAS No.:2873-37-2
Molecular Formula:C20H28N2O5
Molecular Weight:376.453
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80433599
Nikkaji Number:J3.246.411D
Wikidata:Q82247782
Mol file:2873-37-2.mol

Synonyms:2873-37-2;(S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate;Z-Pro-Leu-OMe;Cbz-pro-leu-OMe;benzyl (2S)-2-[[(2S)-1-methoxy-4-methyl-1-oxopentan-2-yl]carbamoyl]pyrrolidine-1-carboxylate;C20H28N2O5;N-Cbz-Pro-Leu-OMe;SCHEMBL11781980;DTXSID80433599;CAA87337;L-Leucine, 1-[(phenylmethoxy)carbonyl]-L-prolyl-, methyl ester;AKOS022175267;DS-4139;CS-0154140;A876643;Methyl 1-[(benzyloxy)carbonyl]-L-prolyl-L-leucinate;(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate

Suppliers and Price of (S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 95+%
25g
$ 212.00

Ambeed
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 95+%
25g
$ 234.00

Ambeed
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 95+%
1g
$ 20.00

Ambeed
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 95+%
5g
$ 70.00

Alichem
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate
100g
$ 609.00

Alichem
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate
25g
$ 205.80

AK Scientific
(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate
25g
$ 343.00

Activate Scientific
N-Cbz-Pro-Leu-OMe 95+% ee
100 g
$ 491.00

Activate Scientific
N-Cbz-Pro-Leu-OMe 95+% ee
25 g
$ 320.00

Activate Scientific
N-Cbz-Pro-Leu-OMe 95+% ee
5 g
$ 104.00

Total 19 raw suppliers

Chemical Property of (S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate

Chemical Property:

Melting Point:76.5-78.0 °C(Solv: ethyl acetate (141-78-6); hexane (110-54-3))
Boiling Point:536.3±50.0 °C(Predicted)
PKA:13.69±0.20(Predicted)
PSA：88.43000
Density:1.171±0.06 g/cm3(Predicted)
LogP:3.26970
Storage Temp.:2-8°C
XLogP3:2.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:9
Exact Mass:376.19982200
Heavy Atom Count:27
Complexity:517

Purity/Quality:

97% ^*data from raw suppliers

(S)-Benzyl2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)CC(C(=O)OC)NC(=O)C1CCCN1C(=O)OCC2=CC=CC=C2
Isomeric SMILES:CC(C)C[C@@H](C(=O)OC)NC(=O)[C@@H]1CCCN1C(=O)OCC2=CC=CC=C2

Technology Process of (S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate

There total 12 articles about (S)-Benzyl 2-(((S)-1-methoxy-4-methyl-1-oxopentan-2-yl)carbamoyl)pyrrolidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 2666-93-5
(S)-Leu-OMe

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 2873-37-2
-L-leucine methyl ester

Guidance literature:: With 1H-imidazole; dicyclohexyl-carbodiimide; In ethyl acetate;
DOI:10.1021/jm00078a009

Reference yield: 90.0%

: 7517-19-3
methyl (L)-leucinate hydrochloride

: 1148-11-4
N-Benzyloxycarbonyl-L-proline

: 2873-37-2
-L-leucine methyl ester

Guidance literature:: With dmap; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1039/b617217b